1
Editorial ranking
Best Urolithin A Supplements 2026: independent ranking by dose, price, testing and evidence
We track 9 Urolithin A products from 7 brands. Every product is scored on the same five-pillar composite: dose honesty, evidence, price per month, third-party testing, and formula transparency. No brand pays for placement. The ranking updates automatically when product data changes.
Independent rankingNo paid placementAuto-updated
Top 10 Urolithin A supplements
2
Runner-up
Urolithin-A Liposomal 1,000mg
Perpetua Life
100%
Matches studies
$1.97
per day
Score: 8.5/10
Tested
3
4
Full Spectrum Urolithin A - 60 capsules
ProHealth Longevity
Score: 7.5/10
50%
Matches studies
$3.73
per day
TestedCoA
5
Timeline Mitopure Gummies (Urolithin A, Strawberry)
Timeline Nutrition
Score: 7.0/10
50%
Matches studies
$8.33
per day
Tested
6
Nutri Urolithin A NAD+ Boost 500mg
Nature's Fusions
Score: 6.6/10
50%
Matches studies
$3.73
per day
7
Creatine+
Elysium Health
Score: 6.4/10
100%
Matches studies
$2.33
per day
8
Urolithin A+
AOR (Advanced Orthomolecular Research)
Score: 6.0/10
100%
Matches studies
$3.21
per day
Tested
9
Detailed comparison
| Rank | Product | Brand | Dose | Price/mo | Tested | Score |
|---|---|---|---|---|---|---|
| 1 | Mitopure® Powder | Timeline Nutrition | 1000 mg | $130.00 | Yes | 8.6 |
| 2 | Urolithin-A Liposomal 1,000mg | Perpetua Life | 1000 mg | $59.00 | Yes | 8.5 |
| 3 | Mitopure® Softgel | Timeline Nutrition | 500 mg | $65.00 | Yes | 7.5 |
| 4 | Full Spectrum Urolithin A - 60 capsules | ProHealth Longevity | 500.0 mg | $55.97 | Yes | 7.5 |
| 5 | Timeline Mitopure Gummies (Urolithin A, Strawberry) | Timeline Nutrition | 500.0 mg | $125.00 | Yes | 7.0 |
| 6 | Nutri Urolithin A NAD+ Boost 500mg | Nature's Fusions | 500 mg | $28.00 | No | 6.6 |
| 7 | Creatine+ | Elysium Health | 300 mg | $70.00 | No | 6.4 |
| 8 | Urolithin A+ | AOR (Advanced Orthomolecular Research) | 1000 mg | $96.44 | Yes | 6.0 |
| 9 | Liposomal Urolithin A | Codeage | 500 mg | $99.99 | Yes | 5.8 |
Scores are editorial judgments, not a scientific standard. See our scoring methodology for how the composite is calculated. Prices are USD and may vary.
What is Urolithin A?
Urolithin A is a postbiotic compound produced when gut bacteria metabolize ellagitannins from pomegranates, walnuts, and berries. Not everyone produces it endogenously; about 40% of adults lack the right gut bacteria. Urolithin A activates mitophagy (selective removal of damaged mitochondria) and has been shown in two published randomized controlled trials to improve muscle endurance and reduce mitochondrial dysfunction in middle-aged adults. It is one of the few longevity-oriented supplements with replicated human trial data showing functional outcomes.
Evidence grade: A. The only longevity ingredient with a replicated RCT showing muscle-strength gains. Read the full evidence review: Urolithin A ingredient page.
How we rank Urolithin A supplements
Every Urolithin A product in our database is scored on five pillars:
- Dose honesty: Does the product contain the amount stated on the label? We check against published third-party assay results when available.
- Evidence: Urolithin A has evidence grade A. Products that cite relevant trials score higher.
- Price per month: Total monthly cost based on label serving recommendations.
- Third-party testing: Does the brand publish a Certificate of Analysis (CoA) from an independent lab?
- Transparency: Is the full formula public? Are all ingredient amounts disclosed?
See the full methodology for the scoring formula.
What to look for in a Urolithin A supplement
- Dose: 250 to 500 mg per day. Clinical trials used 500 mg urolithin A daily for 4 weeks.
- Form: Pure urolithin A is the only form with human trial data. Pomegranate extract is not equivalent; it requires specific gut bacteria to convert.
- Purity: Look for products with published CoA showing 98%+ purity urolithin A.
- Price: Urolithin A is expensive to manufacture. Prices range from $40 to $80+ per month.
- Testing: Third-party testing is essential given the high price point and limited manufacturers.
See the full Urolithin A evidence page for dosing, safety, and landmark studies.
Frequently asked questions
How often is this ranking updated?
Our database checks product prices, availability, and testing status continuously. The ranking recalculates whenever product data changes. The "last updated" date on each product page reflects the most recent verified change.
Do brands pay for placement on this list?
No. We do not accept payment for ranking position. Brands can purchase clearly labeled ad slots, but these never appear in or influence editorial rankings. See our advertising policy.
What dose of Urolithin A should I take?
Dosing depends on the ingredient. See the Urolithin A ingredient page for the trial dose, range, and safety data.
Is Urolithin A safe?
Urolithin A has evidence grade A. Read the safety section on the ingredient page for known interactions and contraindications.