Black Cohosh · Actaea racemosa (Cimicifuga racemosa)
A menopause herb flagged by EU regulators for liver toxicity risk in supplements.
Short answer
Black Cohosh (Actaea racemosa (Cimicifuga racemosa)) is a botanical with evidence grade C, meaning it is backed by mixed or small human trials. We track 0 produkter containing Black Cohosh. The top-ranked product scores 0 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $0.00 per månad.
What it is
Black cohosh is a North American plant used traditionally for menopause symptoms. It is one of the most widely used botanical supplements for women's health.
Why people take it
Human trials show modest benefit for menopausal hot flashes. However, case reports of liver toxicity have raised safety concerns.
Our verdict
Not a longevity ingredient. EU regulators have prioritized it for restriction due to hepatotoxicity case reports.
Structure & class
Actaea racemosa root. Contains triterpene glycosides (actein, cimifugoside) and phenolic acids.
Mechanism & clinical data
Meta-analyses show modest benefit for vasomotor symptoms. Hepatotoxicity case reports led to labeling requirements in several countries.
Pharmacokinetics
Not well characterized.
Dose & forms
What to watch out for
Liver toxicity reported. Discontinue if jaundice or abdominal pain occurs.
Where this dose comes from
The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.
When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.
Regelverk status
Timeline
Regelverk events, evidence grade changes, and key research milestones for Black Cohosh, most recent first. Every entry links to its primär source.
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EU Court sharpens the bar for botanical health claimsA Court of Justice of the European Union ruling in april 2025 further tightened the requirements for how botanical ingredients (herbs, plant extracts) can be marketed with health claims in the EU, effectively removing much of the flexibility of the on-hold list.
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EU heads of food safety agencies prioritize black cohosh for restrictionThe HoA Working Group on Food Supplements identified Actaea racemosa (black cohosh) among 12 substances prioritized for Article 8 restriction due to liver toxicity case reports.
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EU report identifies 117 supplement substances as potential health risksThe HoA Working Group on Food Supplements (26 European countries) published its first report evaluating 117 substances used in food supplements. Of these, 65 were assessed as likely novel foods, 6 were already regulated, 34 had insufficient data, and 12 were prioritized for Article 8 restriction under Regulation (EC) No 1925/2006. The 12 priority substances include ashwagandha, curcumin, melatonin, piperine, St. John's wort, coumarin, p-synephrine, maca, holy basil, Melaleuca, black cohosh, and L-tryptophan. The report drew on 1,500 RASFF alerts reviewed between 2017 and mid-2022.
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HoA 2024 (BVL/NVWA, EU)26-country EU working group prioritized black cohosh (Actaea racemosa) for Article 8 restriction due to liver toxicity case reports and potential health risks.
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EU Health Claims Regulation adoptedRegulation (EC) No 1924/2006 laid down harmonised rules for nutrition and health claims made on foods, including supplements. Only claims listed in the EU Register of authorised claims can be used. Rejected botanical claims are held in a separate on-hold list.
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EU introduces the Novel Food RegulationRegulation (EC) No 258/97 required any food or food ingredient without a history of consumption in the EU before 15 maj 1997 to be authorised before being placed on the market. This is the framework that captures NMN, spermidine as a supplement ingredient, urolithin A, and many other longevity actives.
Landmark studies
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HoA 2024 (BVL/NVWA, EU)
26-country EU working group prioritized black cohosh (Actaea racemosa) for Article 8 restriction due to liver toxicity case reports and potential health risks.
Läs studie →
Found in these produkter
Alla produkter in our catalog that contain Black Cohosh, ranked by our overall score. Ranking is editorial, never paid.
No produkter in our catalog contain this yet.
Buying guides and comparisons
Related ingredients
Se alla in Botanical →Molekyler in the same class, plus the actives most often formulated alongside Black Cohosh in our catalogue.
Frequently asked questions
What is Black Cohosh?
Black cohosh is a North American plant used traditionally for menopause symptoms. It is one of the most widely used botanical supplements for women's health.
What dose of Black Cohosh should I take?
The trial dose in published human studies is 40 mg per dag, with a range of 20 to 80 mg per dag. Always consult a qualified clinician before starting any supplement.
Is Black Cohosh safe?
Liver toxicity reported. Discontinue if jaundice or abdominal pain occurs.
What is the best Black Cohosh supplement?
We track 0 produkter containing Black Cohosh. The top-ranked product scores 0 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.
What is the evidence grade for Black Cohosh?
Black Cohosh has evidence grade C, meaning it is backed by mixed or small human trials. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.
Data verification
Bevisning grades are reviewed when new human RCTs are published. Product counts update automatically as new produkter are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.