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Botanical / Anti-inflammatory

Boswellia · Boswellia serrata Extract

Frankincense resin extract with real, if modest, osteoarthritis trial data at standardized doses.

C
Bevisning grade
Mixed / small human trials

Short answer

Boswellia (Boswellia serrata Extract) is a botanical / anti-inflammatory with evidence grade C, meaning it is backed by mixed or small human trials. We track 0 produkter containing Boswellia. The top-ranked product scores 0 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $0.00 per månad.

Bevisning grade: C Produkter in database: 0 Kategori: Botanical / Anti-inflammatory

What it is

An extract from the resin of the Boswellia tree (frankincense). The active compounds are boswellic acids, especially AKBA.

Why people take it

Randomized trials using extracts standardized for boswellic acids show reduced knee osteoarthritis pain and improved function versus placebo, sometimes within weeks. Trials are short and mostly from a few research groups.

Our verdict

One of the better-evidenced botanical anti-inflammatories — provided the extract is standardized for AKBA.

Structure & class

Gum resin extract standardized to boswellic acids. AKBA inhibits 5-lipoxygenase, reducing leukotriene synthesis.

Mechanism & clinical data

A 2024 trial of a standardized Boswellia serrata extract reported significant WOMAC improvements vs placebo in knee OA. A pilot RCT (Sengupta et al.) of 5-Loxin (AKBA-enriched) showed pain reduction at 90 days. Bevisning base is concentrated in a handful of proprietary extracts; independent replication is limited.

Pharmacokinetics

AKBA plasma half-life ~6 hours; twice-daily dosing typical.

Dose & forms

Trial dose
300 mg
/ day
Range in trials
100 to 400 mg
/ day
Common forms
AKBA-standardized extract (5-Loxin, AprèsFlex), Generic resin extract

What to watch out for

Generic 'boswellia 65%' produkter are not the extracts used in the positive trials. Standardization to AKBA is the quality marker.

Where this dose comes from

The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.

When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.

Regelverk status

EUTraditional use / supplement
USDietary supplement
UKPermitted
CANHP monographed

Timeline

Regelverk events, evidence grade changes, and key research milestones for Boswellia, most recent first. Every entry links to its primär source.

  • 2025-04 Regelverk single source
    EU Court sharpens the bar for botanical health claims
    A Court of Justice of the European Union ruling in april 2025 further tightened the requirements for how botanical ingredients (herbs, plant extracts) can be marketed with health claims in the EU, effectively removing much of the flexibility of the on-hold list.
  • 2024-06 Regelverk confirmed
    EU report identifies 117 supplement substances as potential health risks
    The HoA Working Group on Food Supplements (26 European countries) published its first report evaluating 117 substances used in food supplements. Of these, 65 were assessed as likely novel foods, 6 were already regulated, 34 had insufficient data, and 12 were prioritized for Article 8 restriction under Regulation (EC) No 1925/2006. The 12 priority substances include ashwagandha, curcumin, melatonin, piperine, St. John's wort, coumarin, p-synephrine, maca, holy basil, Melaleuca, black cohosh, and L-tryptophan. The report drew on 1,500 RASFF alerts reviewed between 2017 and mid-2022.
  • 2024 Research milestone
    Standardized extract RCT 2024
    Randomized placebokontrollerad trial of standardized Boswellia extract: significant improvement in knee osteoarthritis pain and function scores.
  • 2006-12 Regelverk confirmed
    EU Health Claims Regulation adopted
    Regulation (EC) No 1924/2006 laid down harmonised rules for nutrition and health claims made on foods, including supplements. Only claims listed in the EU Register of authorised claims can be used. Rejected botanical claims are held in a separate on-hold list.
  • 1997 Regelverk confirmed
    EU introduces the Novel Food Regulation
    Regulation (EC) No 258/97 required any food or food ingredient without a history of consumption in the EU before 15 maj 1997 to be authorised before being placed on the market. This is the framework that captures NMN, spermidine as a supplement ingredient, urolithin A, and many other longevity actives.
  • Research milestone
    Sengupta et al. pilot RCT
    Pilot RCT of AKBA-enriched Boswellia: reduced knee OA pain vs placebo within 90 days.

Landmark studies

  • Standardized extract RCT 2024

    Randomized placebokontrollerad trial of standardized Boswellia extract: significant improvement in knee osteoarthritis pain and function scores.

    Läs studie →
  • Sengupta et al. pilot RCT

    Pilot RCT of AKBA-enriched Boswellia: reduced knee OA pain vs placebo within 90 days.

    Läs studie →

Found in these produkter

Alla produkter in our catalog that contain Boswellia, ranked by our overall score. Ranking is editorial, never paid.

No produkter in our catalog contain this yet.

Redaktionellt guides

Buying guides and comparisons

Neighbouring molecules

Related ingredients

Se alla in Botanical / Anti-inflammatory →

Molekyler in the same class, plus the actives most often formulated alongside Boswellia in our catalogue.

Nothing else in the database sits close enough to this molecule to list.

Frequently asked questions

What is Boswellia?

An extract from the resin of the Boswellia tree (frankincense). The active compounds are boswellic acids, especially AKBA.

What dose of Boswellia should I take?

The trial dose in published human studies is 300 mg per dag, with a range of 100 to 400 mg per dag. Always consult a qualified clinician before starting any supplement.

Is Boswellia safe?

Generic 'boswellia 65%' produkter are not the extracts used in the positive trials. Standardization to AKBA is the quality marker.

What is the best Boswellia supplement?

We track 0 produkter containing Boswellia. The top-ranked product scores 0 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.

What is the evidence grade for Boswellia?

Boswellia has evidence grade C, meaning it is backed by mixed or small human trials. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.

Independently checked

Data verification

Bevisning grade
C
Mixed / small human trials
Research dose
300 mg
Verified n/a
Produkter tracked
0
Uppdaterad continuously
Säkerhet signal
Generic 'boswellia 65%' produkter are not the extracts use...
Verified n/a

Bevisning grades are reviewed when new human RCTs are published. Product counts update automatically as new produkter are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.