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Foundational

Iron · Iron (bisglycinate/ferrous)

Only take if deficient; excess is harmful.

A
Bevisning grade
Replicated human RCTs with hard endpoints

Short answer

Iron (Iron (bisglycinate/ferrous)) is a foundational with evidence grade A, meaning it is well-supported by replicated human trials. We track 1 produkter containing Iron. Typical doses range from 3.98 to 3.98 mg per portion. The top-ranked product scores 5.6 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $90.00 per månad.

Bevisning grade: A Produkter in database: 1 Kategori: Foundational

Top Iron produkter

ProductVarumärkeDosePris/mo3rd-party testedPoäng
Mosaic3.98 mg$90.00No5.6

Scores are editorial judgments, not a scientific standard. Se how we score.

What it is

Essential mineral for oxygen transport in blood.

Why people take it

Deficiency causes anemia; excess causes oxidative stress, especially in men and postmenopausal women.

Our verdict

Test ferritin first. Don't take multivitamins with iron 'just in case'.

Structure & class

Ferrous vs ferric; bisglycinate best absorbed, gentlest.

Mechanism & clinical data

Iron overload common in HFE mutations.

Pharmacokinetics

Weeks.

Dose & forms

Trial dose
25 mg
/ day
Range in trials
25 to 65 mg
/ day
Common forms
Bisglycinate, Ferrous fumarate, Ferrous sulfate

What to watch out for

Don't supplement without testing. Vitamin C boosts absorption.

Where this dose comes from

The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.

When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.

Regelverk status

EUFood supplement
USDietary supplement
UKFood supplement
CANHP

Timeline

Regelverk events, evidence grade changes, and key research milestones for Iron, most recent first. Every entry links to its primär source.

  • 2025-04 Regelverk single source
    EU Court sharpens the bar for botanical health claims
    A Court of Justice of the European Union ruling in april 2025 further tightened the requirements for how botanical ingredients (herbs, plant extracts) can be marketed with health claims in the EU, effectively removing much of the flexibility of the on-hold list.
  • 2024-06 Regelverk confirmed
    EU report identifies 117 supplement substances as potential health risks
    The HoA Working Group on Food Supplements (26 European countries) published its first report evaluating 117 substances used in food supplements. Of these, 65 were assessed as likely novel foods, 6 were already regulated, 34 had insufficient data, and 12 were prioritized for Article 8 restriction under Regulation (EC) No 1925/2006. The 12 priority substances include ashwagandha, curcumin, melatonin, piperine, St. John's wort, coumarin, p-synephrine, maca, holy basil, Melaleuca, black cohosh, and L-tryptophan. The report drew on 1,500 RASFF alerts reviewed between 2017 and mid-2022.
  • 2006-12 Regelverk confirmed
    EU Health Claims Regulation adopted
    Regulation (EC) No 1924/2006 laid down harmonised rules for nutrition and health claims made on foods, including supplements. Only claims listed in the EU Register of authorised claims can be used. Rejected botanical claims are held in a separate on-hold list.
  • 1997 Regelverk confirmed
    EU introduces the Novel Food Regulation
    Regulation (EC) No 258/97 required any food or food ingredient without a history of consumption in the EU before 15 maj 1997 to be authorised before being placed on the market. This is the framework that captures NMN, spermidine as a supplement ingredient, urolithin A, and many other longevity actives.

Landmark studies

    Found in these produkter (1)

    Alla produkter in our catalog that contain Iron, ranked by our overall score. Ranking is editorial, never paid.

    Redaktionellt guides

    Buying guides and comparisons

    Neighbouring molecules

    Related ingredients

    Se alla in Foundational →

    Molekyler in the same class, plus the actives most often formulated alongside Iron in our catalogue.

    Omega-3 (EPA/DHA)Asame categoryVitamin D3Asame categoryVitamin K2Bsame categoryMagnesiumAsame categoryVitamin B12Asame categoryFolate (5-MTHF)Bsame categoryZincAsame categorySeleniumAsame category

    Frequently asked questions

    What is Iron?

    Essential mineral for oxygen transport in blood.

    What dose of Iron should I take?

    The trial dose in published human studies is 25 mg per dag, with a range of 25 to 65 mg per dag. Always consult a qualified clinician before starting any supplement.

    Is Iron safe?

    Don't supplement without testing. Vitamin C boosts absorption.

    What is the best Iron supplement?

    We track 1 produkter containing Iron. The top-ranked product scores 5.6 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.

    What is the evidence grade for Iron?

    Iron has evidence grade A, meaning it is well-supported by replicated human trials. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.

    Independently checked

    Data verification

    Bevisning grade
    A
    Replicated human RCTs with hard endpoints
    Research dose
    25 mg
    Verified n/a
    Produkter tracked
    1
    Uppdaterad continuously
    Säkerhet signal
    Don't supplement without testing. Vitamin C boosts absorp...
    Verified n/a

    Bevisning grades are reviewed when new human RCTs are published. Product counts update automatically as new produkter are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.