Myo-Inositol · Myo-Inositol
A carbocyclic sugar that acts as a second messenger in insulin and serotonin signaling pathways.
Short answer
Myo-Inositol (Myo-Inositol) is a sugar alcohol / signaling molecule with evidence grade B, meaning it is supported by human RCTs. We track 1 produkter containing Myo-Inositol. Typical doses range from 1000 to 1000 mg per portion. The top-ranked product scores 6.5 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $99.00 per månad.
Top Myo-Inositol produkter
| Product | Varumärke | Dose | Pris/mo | 3rd-party tested | Poäng |
|---|---|---|---|---|---|
| AGZ: Nightly Sleep Support | 1000 mg | $99.00 | Yes | 6.5 |
Scores are editorial judgments, not a scientific standard. Se how we score.
What it is
Myo-inositol is a sugar-like molecule found in fruits and grains. It helps cells communicate, especially in insulin and serotonin pathways.
Why people take it
Higher doses (2-4g) can improve insulin sensitivity and may help with mood and sleep. Also studied for PCOS.
Our verdict
Solid evidence for insulin sensitivity and PCOS. Emerging evidence for mood and sleep support. Very safe.
Structure & class
Myo-inositol is a carbocyclic sugar that serves as a second messenger in the phosphatidylinositol signaling pathway. It mediates insulin signaling and serotonin receptor function.
Mechanism & clinical data
RCTs show improvements in insulin sensitivity markers at 2-4g/day. Meta-analyses support efficacy in PCOS. Mood studies show benefit in anxiety and OCD-spectrum conditions.
Pharmacokinetics
Not well characterized; urinary excretion within 24 hours.
Dose & forms
What to watch out for
Generally very safe. maj cause mild GI effects at high doses. Quality varies little between brands as it is a simple molecule.
Where this dose comes from
The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.
When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.
Regelverk status
Timeline
Regelverk events, evidence grade changes, and key research milestones for Myo-Inositol, most recent first. Every entry links to its primär source.
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EU Court sharpens the bar for botanical health claimsA Court of Justice of the European Union ruling in april 2025 further tightened the requirements for how botanical ingredients (herbs, plant extracts) can be marketed with health claims in the EU, effectively removing much of the flexibility of the on-hold list.
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EU report identifies 117 supplement substances as potential health risksThe HoA Working Group on Food Supplements (26 European countries) published its first report evaluating 117 substances used in food supplements. Of these, 65 were assessed as likely novel foods, 6 were already regulated, 34 had insufficient data, and 12 were prioritized for Article 8 restriction under Regulation (EC) No 1925/2006. The 12 priority substances include ashwagandha, curcumin, melatonin, piperine, St. John's wort, coumarin, p-synephrine, maca, holy basil, Melaleuca, black cohosh, and L-tryptophan. The report drew on 1,500 RASFF alerts reviewed between 2017 and mid-2022.
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EU Health Claims Regulation adoptedRegulation (EC) No 1924/2006 laid down harmonised rules for nutrition and health claims made on foods, including supplements. Only claims listed in the EU Register of authorised claims can be used. Rejected botanical claims are held in a separate on-hold list.
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Levine et al. 2001 (Bipolar Disord)Myo-inositol showed efficacy as an adjunct treatment in mood disorders.
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EU introduces the Novel Food RegulationRegulation (EC) No 258/97 required any food or food ingredient without a history of consumption in the EU before 15 maj 1997 to be authorised before being placed on the market. This is the framework that captures NMN, spermidine as a supplement ingredient, urolithin A, and many other longevity actives.
Landmark studies
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Levine et al. 2001 (Bipolar Disord)
Myo-inositol showed efficacy as an adjunct treatment in mood disorders.
Läs studie →
Found in these produkter (1)
Alla produkter in our catalog that contain Myo-Inositol, ranked by our overall score. Ranking is editorial, never paid.
Buying guides and comparisons
Related ingredients
Se alla in Sugar alcohol / signaling molecule →Molekyler in the same class, plus the actives most often formulated alongside Myo-Inositol in our catalogue.
Frequently asked questions
What is Myo-Inositol?
Myo-inositol is a sugar-like molecule found in fruits and grains. It helps cells communicate, especially in insulin and serotonin pathways.
What dose of Myo-Inositol should I take?
The trial dose in published human studies is 2000 mg per dag, with a range of 1000 to 4000 mg per dag. Always consult a qualified clinician before starting any supplement.
Is Myo-Inositol safe?
Generally very safe. maj cause mild GI effects at high doses. Quality varies little between brands as it is a simple molecule.
What is the best Myo-Inositol supplement?
We track 1 produkter containing Myo-Inositol. The top-ranked product scores 6.5 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.
What is the evidence grade for Myo-Inositol?
Myo-Inositol has evidence grade B, meaning it is supported by human RCTs. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.
Data verification
Bevisning grades are reviewed when new human RCTs are published. Product counts update automatically as new produkter are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.