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Microbiome

Probiotics · Probiotic strains

Strain-specific benefits; forget 'total CFU' marketing.

B
Bevisning grade
Human RCTs, biomarker outcomes

Short answer

Probiotics (Probiotic strains) is a microbiome with evidence grade B, meaning it is supported by human RCTs. We track 4 produkter containing Probiotics. Typical doses range from 100.0 to 900 mg per portion. The top-ranked product scores 6.4 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $99.00 per månad.

Bevisning grade: B Produkter in database: 4 Kategori: Microbiome

Top Probiotics produkter

ProductVarumärkeDosePris/mo3rd-party testedPoäng
DS-01® Daily Synbiotic900 mg$60.00Yes6.4
AG1 Foundational Nutrition500 mg$99.00Yes5.9
Seed PM-02 Sleep + Restore200.0 mg$34.99Yes5.4
Seed AM-02 Energy + Focus100.0 mg$34.99Yes5.4

Scores are editorial judgments, not a scientific standard. Se how we score.

What it is

Live bacteria that transit or colonize your gut. Effects are strain-specific, not species-specific, L. rhamnosus GG and L. plantarum 299v do very different things.

Why people take it

Specific strains have RCTs for diarrhea, IBS, atopic disease. Generic 'probiotic' produkter lack specific-strain evidence.

Our verdict

Only take probiotics tied to specific strain-RCT evidence. Ignore CFU count marketing.

Structure & class

Live microbes at labelled CFU count at expiry.

Mechanism & clinical data

Strain-specific evidence documented in AGA and BSG guidelines.

Pharmacokinetics

Transit-dependent.

Dose & forms

Trial dose
0 mg
/ day
Range in trials
0 to 0 mg
/ day
Common forms
Capsule (refrigerated), Shelf-stable, Fermented food

What to watch out for

Refrigerated ≠ better if the strain is shelf-stable. Look for CFU at expiry, not at manufacture.

Where this dose comes from

The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.

When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.

Regelverk status

EUFood supplement (some strains Novel Food)
USDietary supplement
UKFood supplement
CANHP

Timeline

Regelverk events, evidence grade changes, and key research milestones for Probiotics, most recent first. Every entry links to its primär source.

  • 2025-04 Regelverk single source
    EU Court sharpens the bar for botanical health claims
    A Court of Justice of the European Union ruling in april 2025 further tightened the requirements for how botanical ingredients (herbs, plant extracts) can be marketed with health claims in the EU, effectively removing much of the flexibility of the on-hold list.
  • 2024-06 Regelverk confirmed
    EU report identifies 117 supplement substances as potential health risks
    The HoA Working Group on Food Supplements (26 European countries) published its first report evaluating 117 substances used in food supplements. Of these, 65 were assessed as likely novel foods, 6 were already regulated, 34 had insufficient data, and 12 were prioritized for Article 8 restriction under Regulation (EC) No 1925/2006. The 12 priority substances include ashwagandha, curcumin, melatonin, piperine, St. John's wort, coumarin, p-synephrine, maca, holy basil, Melaleuca, black cohosh, and L-tryptophan. The report drew on 1,500 RASFF alerts reviewed between 2017 and mid-2022.
  • 2006-12 Regelverk confirmed
    EU Health Claims Regulation adopted
    Regulation (EC) No 1924/2006 laid down harmonised rules for nutrition and health claims made on foods, including supplements. Only claims listed in the EU Register of authorised claims can be used. Rejected botanical claims are held in a separate on-hold list.
  • 1997 Regelverk confirmed
    EU introduces the Novel Food Regulation
    Regulation (EC) No 258/97 required any food or food ingredient without a history of consumption in the EU before 15 maj 1997 to be authorised before being placed on the market. This is the framework that captures NMN, spermidine as a supplement ingredient, urolithin A, and many other longevity actives.

Landmark studies

    Found in these produkter (4)

    Alla produkter in our catalog that contain Probiotics, ranked by our overall score. Ranking is editorial, never paid.

    Redaktionellt guides

    Buying guides and comparisons

    Neighbouring molecules

    Related ingredients

    Se alla in Microbiome →

    Molekyler in the same class, plus the actives most often formulated alongside Probiotics in our catalogue.

    Prebiotic FiberBsame categoryAkkermansiaCsame categoryRiboflavin (B2)Bstacked together in 2 produkterQuercetinBstacked together in 2 produkterGreens blendDstacked together in 1 productAdaptogen blendDstacked together in 1 productVitamin CAstacked together in 1 productMelatoninAstacked together in 1 product

    Frequently asked questions

    What is Probiotics?

    Live bacteria that transit or colonize your gut. Effects are strain-specific, not species-specific, L. rhamnosus GG and L. plantarum 299v do very different things.

    What dose of Probiotics should I take?

    The trial dose in published human studies is 0 mg per dag, with a range of 0 to 0 mg per dag. Always consult a qualified clinician before starting any supplement.

    Is Probiotics safe?

    Refrigerated ≠ better if the strain is shelf-stable. Look for CFU at expiry, not at manufacture.

    What is the best Probiotics supplement?

    We track 4 produkter containing Probiotics. The top-ranked product scores 6.4 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.

    What is the evidence grade for Probiotics?

    Probiotics has evidence grade B, meaning it is supported by human RCTs. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.

    Independently checked

    Data verification

    Bevisning grade
    B
    Human RCTs, biomarker outcomes
    Research dose
    0 mg
    Verified n/a
    Produkter tracked
    4
    Uppdaterad continuously
    Säkerhet signal
    Refrigerated ≠ better if the strain is shelf-stable. Look...
    Verified n/a

    Bevisning grades are reviewed when new human RCTs are published. Product counts update automatically as new produkter are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.