Resveratrol · trans-Resveratrol
The famous red-wine molecule; longevity claims have outrun the human evidence.
Short answer
Resveratrol (trans-Resveratrol) is a polyphenol / sirtuin activator with evidence grade C, meaning it is backed by mixed or small human trials. We track 30 produkter containing Resveratrol. Typical doses range from 12.5 to 1000.0 mg per portion. The top-ranked product scores 6.7 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $105.00 per månad.
Top Resveratrol produkter
| Product | Varumärke | Dose | Pris/mo | 3rd-party tested | Poäng |
|---|---|---|---|---|---|
| Trans-Resveratrol Plus - 1000 mg per portion | 1000.0 mg | $31.08 | Yes | 6.7 | |
| NMN + Resveratrol | 500 mg | $59.97 | Yes | 6.7 | |
| Resveratrol Supplement (Trans-Resveratrol) | 500.0 mg | $19.95 | Yes | 6.6 | |
| ResveraCel | 150 mg | $105.00 | Yes | 6.6 | |
| Lemme NAD+ | 100 mg | $50.00 | No | 6.4 |
Scores are editorial judgments, not a scientific standard. Se how we score.
What it is
A compound made by plants under stress (grape skins, Japanese knotweed). In lab animals fed high doses, it mimics some of the effects of eating less food, a well-established longevity intervention.
Why people take it
Mouse and yeast studies are impressive. Human studies are mixed: some show improvements in insulin sensitivity or blood-vessel function, others show nothing. Absorption is poor, most of what you swallow gets broken down before it reaches your cells.
Our verdict
Overhyped but not useless. If you take it, choose produkter that use trans-resveratrol (not blends) and pair with a fatty meal for absorption.
Structure & class
3,5,4'-trihydroxy-trans-stilbene. SIRT1 activator (contested), AMPK modulator, phytoalexin.
Mechanism & clinical data
Yeast and murine models show lifespan extension in high-fat contexts. Human trials mixed; RESHAW (2020) failed to replicate cognitive benefits. Bioavailability <1% oral; extensive first-pass sulfation/glucuronidation.
Pharmacokinetics
~2 hours; metabolites persist longer.
Dose & forms
What to watch out for
"Resveratrol" produkter that don't specify trans-isomer content are unmeasurable in practice. Cis-resveratrol is biologically inactive.
Säkerhet limits and interactions
When a product exceeds the UL or contains an ingredient with clinically significant interactions, a "Review advised" flag appears on its product page and links here.
Source: https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/resveratrol
Where this dose comes from
The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.
When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.
Regelverk status
Timeline
Regelverk events, evidence grade changes, and key research milestones for Resveratrol, most recent first. Every entry links to its primär source.
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Lozupone 2026 (Expert Opin Investig Drugs)26-year critical review of longevity pharmacology. Despite rapid mechanistic advances in senolytics, autophagy modulators, and metabolic pathway targets, clinical translation remains uncertain.
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EU Court sharpens the bar for botanical health claimsA Court of Justice of the European Union ruling in april 2025 further tightened the requirements for how botanical ingredients (herbs, plant extracts) can be marketed with health claims in the EU, effectively removing much of the flexibility of the on-hold list.
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EU report identifies 117 supplement substances as potential health risksThe HoA Working Group on Food Supplements (26 European countries) published its first report evaluating 117 substances used in food supplements. Of these, 65 were assessed as likely novel foods, 6 were already regulated, 34 had insufficient data, and 12 were prioritized for Article 8 restriction under Regulation (EC) No 1925/2006. The 12 priority substances include ashwagandha, curcumin, melatonin, piperine, St. John's wort, coumarin, p-synephrine, maca, holy basil, Melaleuca, black cohosh, and L-tryptophan. The report drew on 1,500 RASFF alerts reviewed between 2017 and mid-2022.
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RESHAW 202012 months of 150 mg twice daily in postmenopausal women showed no cognitive benefit.
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EU authorizes trans-resveratrol as Novel FoodThe European Commission authorized trans-resveratrol as a Novel Food under Regulation (EU) 2016/1866. Synthetic and fermentation-derived trans-resveratrol are permitted in food supplements at specified maximum levels. Grape-extracted resveratrol was already on the market.
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Timmers et al. 2011 (Cell Metabolism)150 mg/day for 30 days improved metabolic profile in obese men.
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EU Health Claims Regulation adoptedRegulation (EC) No 1924/2006 laid down harmonised rules for nutrition and health claims made on foods, including supplements. Only claims listed in the EU Register of authorised claims can be used. Rejected botanical claims are held in a separate on-hold list.
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EU introduces the Novel Food RegulationRegulation (EC) No 258/97 required any food or food ingredient without a history of consumption in the EU before 15 maj 1997 to be authorised before being placed on the market. This is the framework that captures NMN, spermidine as a supplement ingredient, urolithin A, and many other longevity actives.
Reported adverse events
Consumer reports submitted to an official government adverse-event database. These reports mention this ingredient but do not prove it caused the reaction. Report volume reflects market penetration as much as inherent risk.
Retrieved from the FDA Adverse Event Reporting System (CAERS) via the openFDA API. Verified 2026-08-06. Reports are voluntary consumer submissions and mandatory serious-event filings. They establish surveillance, not causality.
Landmark studies
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Timmers et al. 2011 (Cell Metabolism)
150 mg/day for 30 days improved metabolic profile in obese men.
Läs studie → -
RESHAW 2020
12 months of 150 mg twice daily in postmenopausal women showed no cognitive benefit.
Läs studie → -
Lozupone 2026 (Expert Opin Investig Drugs)
26-year critical review of longevity pharmacology. Despite rapid mechanistic advances in senolytics, autophagy modulators, and metabolic pathway targets, clinical translation remains uncertain.
Läs studie →
Found in these produkter (30)
Alla produkter in our catalog that contain Resveratrol, ranked by our overall score. Ranking is editorial, never paid.
Buying guides and comparisons
Related ingredients
Se alla in Polyphenol / Sirtuin activator →Molekyler in the same class, plus the actives most often formulated alongside Resveratrol in our catalogue.
Frequently asked questions
What is Resveratrol?
A compound made by plants under stress (grape skins, Japanese knotweed). In lab animals fed high doses, it mimics some of the effects of eating less food, a well-established longevity intervention.
What dose of Resveratrol should I take?
The trial dose in published human studies is 500 mg per dag, with a range of 150 to 1000 mg per dag. Always consult a qualified clinician before starting any supplement.
Is Resveratrol safe?
"Resveratrol" produkter that don't specify trans-isomer content are unmeasurable in practice. Cis-resveratrol is biologically inactive.
What is the best Resveratrol supplement?
We track 30 produkter containing Resveratrol. The top-ranked product scores 6.7 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.
What is the evidence grade for Resveratrol?
Resveratrol has evidence grade C, meaning it is backed by mixed or small human trials. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.
Data verification
Bevisning grades are reviewed when new human RCTs are published. Product counts update automatically as new produkter are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.