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Berberin HCl Powder

Metabolic · Powder · 100 portioner#8 / 18 in Metabolic
6.5
Overall score · out of 10
6.5
Overall score · out of 10
Dose vs. studies6.4
Transparency6.0
Value9.1
Community6.0
Formulation5.0
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
Redaktionellt score, paid $0 No affiliate link No third-party test No public analysintyg Sample received: No
How we scored this product Show the full breakdown
Composite How this 6.5 is built. 0.55 × 6.4 + 0.20 × 6.0 + 0.10 × 9.1 + 0.10 × 6.0 + 0.05 × 5.0 = 6.5 out of 10. Säkerhet caps applied after. 6.5
6.5 composite
Dose vs. studies55%6.4
Transparency20%6.0
Value10%9.1
Community10%6.0
Formulation5%5.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Plant-derived AMPK activator; near-drug-strength effects on blood sugar and lipids.

1 landmark RCT · US: Dietary supplement · EU: Restricted in Italy (drug status ≥10 mg); food supplement elsewhere
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
33% av studiedosen
Well below the trial dose
Cost at trial dose
$0.72/day at trial dose
What one effective daily dose actually costs
Transparency
6.0/10 · No public analysintyg
No third-party testing disclosed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

Säkerhet signals
Drug interaction risk — berberine
Berberin inhibits CYP3A4, CYP2D6, and CYP2C9 even at moderate doses. Documented interactions with immunosuppressants, statins, anticoagulants, and antidiabetic drugs. Consult a physician if taking prescription medications.
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No public analysintyg
Certificate of Analysis not published
Without a public analysintyg, batch purity and potency cannot be independently verified.
No third-party testing
Independent lab verification not disclosed
The brand does not publish evidence of independent batch testing.
Underdosed
Dose at 33% av studiedosen
Below 50% of the dose used in published clinical trials.
Buyer complaints
Trustpilot: customer service complaints on some orders
Recurring themes from consumer review platforms.
Redaktionellt verdict

Quick verdict

6.5 / 10
Best for
Budget-friendly
Avoid if
Only 33% av studiedosen, No public analysintyg
Full-dose status
33% av studiedosen
Pris/month
$7
COA status
Not public
Biggest caveat
Dose is 33% of the trial dose.
Nearest alternatives

The numbers

Pris
$24
per bottle · 100 portioner
Dose vs. research
Below trial dose 33%
of published effective dose
$ / day at studied dose
$0.72
what one effective daily dose costs
$ / g active
$0.48
per gram of active substance
Independently checked

Data verification

Pris
$24
Verified n/a
Dose
33% av studiedosen
Verified n/a
COA status
Not public
Verified n/a
Bevisning grade
A
Per-ingredient breakdown
ABerberin
Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Bevisning
Berberin
Plant-derived AMPK activator; near-drug-strength effects on blood sugar and lipids.
500.0 mg 33% av studiedosen
1500 mg

Consumer signals

Consumer signals gathered from 2 platforms.

Medium confidence

positive sentiment

Praisegood value bulk powdersupports blood sugar management
ThemesAmazon listing markets BulkSupplements Berberin HCl for metabolic and blood sugar support at a bulk-powder price point.

Compiled from a Amazon product listing listing located during research; verified at build time.

415 reviews · mixed sentiment

Praiseproduct effectiveness and puritycompetitive pricing
Complaintscustomer service complaints on some orders
ThemesBulkSupplements' Trustpilot profile shows most reviewers were somewhat happy overall, with quality and pricing praised but some customer service issues noted.

Compiled from a Trustpilot listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Bevisning

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Important to know
BerberinStandard berberine has ~5% oral bioavailability. Dihydroberberine and berberine phytosomes absorb better. Split doses across meals (500 mg × 3) to avoid GI upset.

Redaktionellt notes

Standard 500mg berberine HCl powder at a competitive price with no absorption-enhancing co-ingredient (e.g. no dihydroberberine or silymarin pairing that some competitors add).

In plain language

Why this scored this way

This BulkSupplements Berberin HCl Powder scores 6.5, making it a mid-tier product with both strengths and weaknesses. It contains 500.0mg of Berberin, which is only 33% of the 1500mg trial dose with grade A evidence (strong human trial data). The quality transparency (6.0) is limited by the lack of third-party testing.

What drives the score up

  • Dose-evidence score of 6.4 shows decent alignment with trial doses.

What drags it down

  • Overall dose is only 33% of the trial dose across ingredients.
  • Berberin (500.0mg is 33% of the 1500mg trial dose) is significantly under-dosed.
  • No third-party testing, which caps the quality transparency.
  • Quality transparency of 6.0 is below the site average.
  • Limited consumer feedback (community score: 6.0).

Why you'd choose it

  • You want good value at $0.72/day.
  • You want Berberin from a BulkSupplements product.

Why you might skip it

  • You want third-party verified purity.
  • You want a product with a publicly available CoA.
  • You need a full trial dose of berberine (this product under-doses it).
Go deeper

Where this sits

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of Berberin HCl Powder and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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