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Glycine & NAC

Amino acid · Capsule · 366 portioner#8 / 11 in Amino acid
6.0
Overall score · out of 10
6.0
Overall score · out of 10
Dose vs. studies5.2
Transparency7.0
Value9.0
Community6.0
Formulation5.0
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
Redaktionellt score, paid $0 No affiliate link Tested by independent lab No public analysintyg Sample received: No
How we scored this product Show the full breakdown
Composite How this 6.0 is built. 0.55 × 5.2 + 0.20 × 7.0 + 0.10 × 9.0 + 0.10 × 6.0 + 0.05 × 5.0 = 6.0 out of 10. Säkerhet caps applied after. 6.0
6.0 composite
Dose vs. studies55%5.2
Transparency20%7.0
Value10%9.0
Community10%6.0
Formulation5%5.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Cheap amino acid with better sleep and glutathione-precursor benefits.

1 landmark RCT · US: Dietary supplement / GRAS · EU: Food supplement

Cysteine donor for glutathione synthesis; drug-strength efficacy for specific uses.

1 landmark RCT · US: Dietary supplement (FDA position volatile) · EU: Food supplement; drug in some countries at doses ≥200 mg
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
10% av studiedosen
Well below the trial dose
Cost at trial dose
$0.82/day at trial dose
What one effective daily dose actually costs
Transparency
7.0/10 · No public analysintyg
Independent batch testing confirmed
Consumer signals
310 reviews across platforms · 4.4/5 · high confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public analysintyg
Certificate of Analysis not published
Without a public analysintyg, batch purity and potency cannot be independently verified.
Underdosed
Dose at 10% av studiedosen
Below 50% of the dose used in published clinical trials.
Buyer complaints
Trustpilot: Occasional shipping delays; Amazon (via Desertcart cross-listing): Unpleasant smell
Recurring themes from consumer review platforms.
Redaktionellt verdict

Quick verdict

6.0 / 10
Best for
Budget-friendly
Avoid if
Only 10% av studiedosen, No public analysintyg
Full-dose status
10% av studiedosen
Pris/month
$2
COA status
Not public
Biggest caveat
Dose is 10% of the trial dose.
Nearest alternatives

The numbers

Pris
$30
per bottle · 366 portioner
Dose vs. research
Below trial dose 10%
of published effective dose
$ / day at studied dose
$0.82
what one effective daily dose costs
$ / g active
$0.14
per gram of active substance
Independently checked

Data verification

Pris
$30
Verified n/a
Dose
10% av studiedosen
Verified n/a
COA status
Not public
Verified n/a
Bevisning grade
BB
Per-ingredient breakdown
BGlycine
BNAC
Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Bevisning
Glycine
Cheap amino acid with better sleep and glutathione-precursor benefits.
300.0 mg 10% av studiedosen
3000 mg
NAC
Cysteine donor for glutathione synthesis; drug-strength efficacy for specific uses.
300.0 mg 50% av studiedosen
600 mg
4.1 /5
High confidence
310 reviews across 3 platforms (3 sources)
Source diversity: 69%
AmazonRedditTrustpilot
PraiseHigh quality and purityBacked by research
ComplaintsOccasional shipping delaysUnpleasant smell
Last checked: 2026-08-07

Consumer signals

4.38 out of 5 across 310 verified reviews on 3 platforms.

High confidence

Consumer sentiment compiled from 3 public sources.

301 reviews · 4.4/5 · positive sentiment

PraiseHigh quality and purityBacked by research
ComplaintsOccasional shipping delays
ThemesDoNotAge's Trustpilot rating is consistently 'Excellent' (4.4-4.6/5) across hundreds of reviews, citing product purity and research backing.

Compiled from Trustpilot listing located during research; verified at build time.

9 reviews · 3.8/5 · mixed sentiment

PraiseNo additivesEasy to swallow
ComplaintsUnpleasant smellSmall review sample
ThemesA smaller international retail listing shows mixed feedback (3.8/5) on smell and additive-free formulation.

Compiled from Amazon (via Desertcart cross-listing) listing located during research; verified at build time.

3 threads discussed · mixed sentiment

PraiseInterest in GlyNAC longevity research
ComplaintsReports of strange side effects in some users
ThemesReddit's r/Supplements and r/healthylongevity discuss GlyNAC supplementation broadly, with some users reporting unexpected side effects.

Compiled from Reddit listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Bevisning

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Important to know
GlycineNone major. Very sweet in powder form, mix in water or coffee.
NACSmells like sulfur (rotten eggs). Enteric-coated forms reduce this. Don't combine with nitrates without medical supervision.

Redaktionellt notes

Convenient combo of the two GlyNAC components, but dosed far lower (300mg each) than the roughly 0.1g/kg-bodyweight doses used in the human GlyNAC aging-biomarker trials.

In plain language

Why this scored this way

This DoNotAge Glycine & NAC scores 6.0, making it below the site average. It delivers 300.0mg of NAC (50% of the 600mg trial dose) with grade B evidence (promising human data, not yet comprehensive).

What drives the score up

  • Tested by independent lab (transparency 7.0).

What drags it down

  • Dose-evidence score of 5.2 is below average for the site.
  • Overall dose is only 10% of the trial dose across ingredients.
  • Glycine (300.0mg is 10% of the 3000mg trial dose) is significantly under-dosed.
  • No public analysintyg available for independent verification.
  • Limited consumer feedback (community score: 6.0).

Why you'd choose it

  • You want a reasonably priced amino acid product.
  • You want NAC from a DoNotAge product.
  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You need a full trial dose of glycine (this product under-doses it).
  • You want a product that hits the full trial dose (this is at 10%).
Go deeper

Where this sits

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of Glycine & NAC and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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