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SIRT6Activator®

Sirtuin activator · Capsule · 366 portioner#17 / 17 in Sirtuin activator
3.5
Overall score · out of 10
3.5
Overall score · out of 10
Dose vs. studies1.0
Transparency7.0
Value6.4
Community6.0
Formulation5.0
Tier 5
Mechanistic / animal / marketing
Only mechanistic studies or marketing claims. No human RCT for this ingredient.
Redaktionellt score, paid $0 No affiliate link Tested by independent lab No public analysintyg Sample received: No
How we scored this product Show the full breakdown
Composite How this 3.5 is built. 0.55 × 1.0 + 0.20 × 7.0 + 0.10 × 6.4 + 0.10 × 6.0 + 0.05 × 5.0 = 3.5 out of 10. Säkerhet caps applied after. 3.5
3.5 composite
Dose vs. studies55%1.0
Transparency20%7.0
Value10%6.4
Community10%6.0
Formulation5%5.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

DoNotAge's proprietary angle; genuinely interesting biology, extremely early evidence.

1 landmark RCT · US: Dietary supplement · EU: Food supplement (seaweed-derived)
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
10% av studiedosen
Well below the trial dose
Cost at trial dose
$2.65/day at trial dose
What one effective daily dose actually costs
Transparency
7.0/10 · No public analysintyg
Independent batch testing confirmed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public analysintyg
Certificate of Analysis not published
Without a public analysintyg, batch purity and potency cannot be independently verified.
Underdosed
Dose at 10% av studiedosen
Below 50% of the dose used in published clinical trials.
Redaktionellt verdict

Quick verdict

3.5 / 10
Best for
Budget-friendly
Avoid if
Only 10% av studiedosen, No public analysintyg
Full-dose status
10% av studiedosen
Pris/month
$8
COA status
Not public
Biggest caveat
Dose is 10% of the trial dose.
Nearest alternatives

The numbers

Pris
$97
per bottle · 366 portioner
Dose vs. research
Below trial dose 10%
of published effective dose
$ / day at studied dose
$2.65
what one effective daily dose costs
$ / g active
$0.66
per gram of active substance
Independently checked

Data verification

Pris
$97
Verified n/a
Dose
10% av studiedosen
Verified n/a
COA status
Not public
Verified n/a
Bevisning grade
E
Per-ingredient breakdown
ESIRT6 Activator
Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Bevisning
SIRT6 Activator
DoNotAge's proprietary angle; genuinely interesting biology, extremely early evidence.
400.0 mg 10% av studiedosen
4000 mg

Consumer signals

Consumer signals gathered from 1 platform.

Medium confidence

150 reviews · positive sentiment

PraiseIncreased energy after combining with NMN over 12 monthsFeeling noticeably better overall150+ verified 5-star Trustpilot reviews cited
ThemesDoNotAge's SIRT6 Activator page cites over 150 verified 5-star Trustpilot reviews, with customer testimonials emphasizing sustained energy gains after months of combined use with NMN.

Compiled from a DoNotAge product page listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Bevisning

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Important to know
SIRT6 ActivatorFucoidan is inexpensive as a seaweed extract. High-priced 'SIRT6 activator' branding doesn't mean higher potency, check fucoidan mg/capsule.

Redaktionellt notes

Branded fucoidan extract sold at a large premium versus generic fucoidan supplements; SIRT6-activation claims rest on in-house/preclinical data rather than published human trials.

In plain language

Why this scored this way

This DoNotAge SIRT6Activator® scores 3.5, making it among the lowest-scoring produkter we track. It contains 400.0mg of SIRT6 Activator, which is only 10% of the 4000mg trial dose with grade E evidence. At $2.65/day it's among the more expensive options in Sirtuin activator.

What drives the score up

  • Tested by independent lab (transparency 7.0).

What drags it down

  • Dose-evidence score of 1.0 is below average for the site.
  • Overall dose is only 10% of the trial dose across ingredients.
  • SIRT6 Activator (400.0mg is 10% of the 4000mg trial dose) is significantly under-dosed.
  • No public analysintyg available for independent verification.
  • Limited consumer feedback (community score: 6.0).

Why you'd choose it

  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You need a full trial dose of sirt6 activator (this product under-doses it).
  • You want a cheaper option (this is $2.65/day).
Go deeper

Where this sits

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of SIRT6Activator® and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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