← Alla produkter

NOVOS Core

All-in-one · Powder sachet · 30 portioner#1 / 3 in All-in-one
6.1
Overall score · out of 10
6.1
Overall score · out of 10
Dose vs. studies6.0
Transparency7.5
Value3.0
Community8.0
Formulation5.0
Tier 1
Product RCT (peer-reviewed)
Strongest evidence: a peer-reviewed RCT tested this exact product.
Redaktionellt score, paid $0 No affiliate link Tested by independent lab No public analysintyg Sample received: No
How we scored this product Show the full breakdown
Composite How this 6.1 is built. 0.55 × 6.0 + 0.20 × 7.5 + 0.10 × 3.0 + 0.10 × 8.0 + 0.05 × 5.0 = 6.1 out of 10. Säkerhet caps applied after. 6.1
6.1 composite
Dose vs. studies55%6.0
Transparency20%7.5
Value10%3.0
Community10%8.0
Formulation5%5.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

A NAD+ building block that has become the most-hyped longevity molecule.

5 landmark RCTs · US: FDA NDI status volatile (juli 2026) · EU: Unauthorised Novel Food (EFSA positive maj 2026, no Commission listing yet)

Trace lithium in drinking water correlates with less dementia in several ecological studies. Nobody has run the trial.

2 landmark RCTs · US: Dietary supplement · EU: Permitted as food supplement (low doses)

Highly-hyped senolytic; the strong evidence is in mice, not people.

3 landmark RCTs · US: Dietary supplement · EU: Food supplement

Resveratrol's more bioavailable cousin, mostly used in blends.

1 landmark RCT · US: Dietary supplement · EU: Food supplement

Classic joint supplement with modest osteoarthritis data and large cohort studies linking regular use to lower mortality.

2 landmark RCTs · US: Dietary supplement · EU: Medicinal product in some member states, supplement in others

The 'calm alertness' amino acid from green tea.

1 landmark RCT · US: GRAS · EU: Food supplement

One of the most common deficiencies; corrects sleep, muscle cramps, and blood pressure.

5 landmark RCTs · US: Dietary supplement · EU: Food supplement, health claims authorised

Cheap amino acid with better sleep and glutathione-precursor benefits.

1 landmark RCT · US: Dietary supplement / GRAS · EU: Food supplement

Skin hydration and joint comfort at 120 mg/day.

1 landmark RCT · US: Dietary supplement · EU: Food supplement

Krebs-cycle intermediate sold as a longevity supplement. Lifespan results exist in mice; human evidence is a single retrospective, company-funded analysis.

2 landmark RCTs · US: Dietary ingredient · EU: Permitted as food supplement

Adaptogen for fatigue and mild stress.

No landmark RCTs listed · US: Dietary supplement · EU: Food supplement

One of the best-evidenced botanicals for nausea. Modest anti-inflammatory data beyond that.

2 landmark RCTs · US: Dietary supplement / GRAS spice · EU: Traditional herbal medicinal product
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
50% av studiedosen
Below the full trial dose
Cost at trial dose
$5.93/day at trial dose
What one effective daily dose actually costs
Transparency
7.5/10 · No public analysintyg
Independent batch testing confirmed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

Säkerhet signals
Drug interaction risk — magnesium
Can reduce absorption/efficacy of oral bisphosphonates, tetracyclines, and quinolone antibiotics.
Läs mer
Drug interaction risk — rhodiola
Theoretical pharmacodynamic interactions with serotonergic drugs, MAOIs, stimulants, anticoagulants, and antihypertensives; may affect CYP-metabolized medications — clinical caution advised with polypharmacy.
Läs mer
No public analysintyg
Certificate of Analysis not published
Without a public analysintyg, batch purity and potency cannot be independently verified.
Redaktionellt verdict

Quick verdict

6.1 / 10
Best for
Basic coverage
Avoid if
Only 50% av studiedosen, No public analysintyg, Premium pricing
Full-dose status
50% av studiedosen
Pris/month
$89
COA status
Not public
Biggest caveat
Dose is 50% of the trial dose.
Nearest alternatives

The numbers

Pris
$89
per bottle · 30 portioner
Dose vs. research
Below trial dose 50%
of published effective dose
$ / day at studied dose
$5.93
what one effective daily dose costs
$ / g active
$0.85
per gram of active substance
Independently checked

Data verification

Pris
$89
Verified n/a
Dose
50% av studiedosen
Verified n/a
COA status
Not public
Verified n/a
Bevisning grade
BDCDCBABBDCB
Per-ingredient breakdown
BNMN
DLithium (microdose)
CFisetin
DPterostilbene
CGlucosamine
BL-Theanine
AMagnesium
BGlycine
BHyaluronic Acid
DCa-AKG
CRhodiola Rosea
BGinger
Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Bevisning
NMN
A NAD+ building block that has become the most-hyped longevity molecule.
250 mg 50% av studiedosen
500 mg
Lithium (microdose)
Trace lithium in drinking water correlates with less dementia in several ecological studies. Nobody has run the trial.
1 mg 100% av studiedosen
1 mg
150 mg 30% av studiedosen
500 mg
Pterostilbene
Resveratrol's more bioavailable cousin, mostly used in blends.
50 mg 50% av studiedosen
100 mg
Glucosamine
Classic joint supplement with modest osteoarthritis data and large cohort studies linking regular use to lower mortality.
500 mg 33% av studiedosen
1500 mg
L-Theanine
The 'calm alertness' amino acid from green tea.
200 mg 100% av studiedosen
200 mg
340 mg 113% av studiedosen
300 mg
Glycine
Cheap amino acid with better sleep and glutathione-precursor benefits.
1000 mg 33% av studiedosen
3000 mg
Hyaluronic Acid
Skin hydration and joint comfort at 120 mg/day.
150 mg 125% av studiedosen
120 mg
Ca-AKG
Krebs-cycle intermediate sold as a longevity supplement. Lifespan results exist in mice; human evidence is a single retrospective, company-funded analysis.
500 mg 50% av studiedosen
1000 mg
Rhodiola Rosea
Adaptogen for fatigue and mild stress.
250 mg 62% av studiedosen
400 mg
Ginger
One of the best-evidenced botanicals for nausea. Modest anti-inflammatory data beyond that.
100 mg 10% av studiedosen
1000 mg
3.8 /5
Medium confidence
Rated on 3 platforms (3 sources, no structured review counts)
Source diversity: 69%
RedditTrustpilotYouTube
PraiseLong-form interview with Chris Mirabile; praises hallmarks-based formulation log4.5/5. Users note taste and packaging as positives.
Last checked: 2026-08-07

Consumer signals

Consumer signals gathered from 3 platforms.

Medium confidence

Consumer sentiment compiled from 3 public sources (Reddit, Trustpilot, YouTube).

1 threads discussed · positive sentiment

PraiseLong-form interview with Chris Mirabile; praises hallmarks-based formulation logic.

Compiled from a YouTube, Modern Healthspan listing located during manual research; not independently re-verified against the live page at build time.

4.5/5 · positive sentiment

Praise4.5/5. Users note taste and packaging as positives.

Compiled from a Trustpilot listing located during manual research; not independently re-verified against the live page at build time.

1 threads discussed · mixed sentiment

ThemesCommunity likes formulation logic but flags cost vs. individual DIY stack.

Compiled from a Reddit r/longevity listing located during manual research; not independently re-verified against the live page at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

Independent external anchors

Public sources on this same product, unrelated to NO1GEVITY. NIH DSLD is the US government's registered label database (shown verbatim). SuppCo.com is a separate, unaffiliated commercial site with no partnership or data-sharing arrangement with us. NO1GEVITY scores are computed independently of both.

Unaffiliated third-party site
SuppCo.com

SuppCo is a separate, unaffiliated supplement-tracking site with no partnership, data-sharing agreement, or business relationship with NO1GEVITY. We are not endorsed by them and they do not endorse us. The two facts below are individually verified against the manufacturer or NSF; the outbound link is provided only so readers can independently cross-check on a third-party site if they want to.

Tested by independent lab, Yes

What others say, with a source hierarchy

We treat external opinion very differently depending on where it comes from. Tier A is our strongest signal. Tier C is background sentiment only. Tier Rejected is what we excluded, listed openly so you can see what we discarded.

These reviews are aggregated from third-party sources, not written by NO1GEVITY. Each entry shows its source, retrieval date, and whether the source has an affiliate or paid relationship. We do not edit reviews to change their meaning. Disclosure policy.

Tier A

Independent deep reviews, lab tests, certificates of analysis

Our strongest external evidence. Long-form independent reviews, physical-product lab work, and third-party certifications.

BetterVitals — NOVOS Core review 2026
unknown Not a paid placement

Structured review of the NOVOS Core stack. Formulation logic praised; notes the lack of an independent human outcome trial on the finished blend and the sponsor funding of NOVOS' own study.

How we use it: Facts on formulation, dose, and study design adopted. Redaktionellt score not adopted.
Longevity Graded — NOVOS Core review
unknown Not a paid placement

Independent review that reaches the same conclusion: NOVOS Core's own study is sponsor-funded and unreplicated; ingredient logic is sound but no product-level outcome trial exists.

How we use it: Confirmatory Tier A source alongside BetterVitals.
Rejected

Sources we transparently discard

Marketing-quoted press, obviously fabricated aggregate ratings, or heavy-affiliate 'reviews'. Listed openly so you can see what we excluded.

Forbes coverage — aggregated by NOVOS as marketing
unknown Not a paid placement

Business journalism aggregated by NOVOS itself for marketing. Not an independent efficacy review.

How we use it: Not used as evidence. Flagged for transparency.

Community threads and aggregate ratings

Additional public mentions we located, kept separate from the deep independent reviews above.

YouTube, Modern Healthspan
positive

Long-form interview with Chris Mirabile; praises hallmarks-based formulation logic.

Read source → Unverified · we received no payment for this listing
Trustpilot · 4.5
positive

4.5/5. Users note taste and packaging as positives.

Read source → Unverified · we received no payment for this listing
Reddit r/longevity
mixed

Community likes formulation logic but flags cost vs. individual DIY stack.

Read source → Unverified · we received no payment for this listing

Vår sammanfattning

NOVOS Core is a 12-ingredient daily powder built around the idea of nudging many aging-related biological pathways at once rather than maximizing one. Its biggest strength, genuinely rare in this product category, is a real randomized, placebokontrollerad human trial on the exact commercial formula (the University of Surrey-led STAMINA study), which found meaningful improvements in blood vessel function and blood pressure over six months — though that trial is still an unpublished preprint awaiting peer review, so its conclusions should be considered promising but not yet fully vetted. A companion mouse study showing an 18% lifespan extension is real work from a credible academic lab, but it's also still an unpublished preprint, and mouse results are a weak guide to what happens in people. Individual ingredient doses inside Core (fisetin, pterostilbene, Ca-AKG, glucosamine, ginger) generally sit well below the doses used in the human or animal studies most often cited for those ingredients, which is the typical tradeoff of combining many actives into one serving. NOVOS's marketing habit of quoting a large aggregate 'number of studies' and drawing loose comparisons to exercise or diet interventions goes further than the underlying science supports, and buyers should weigh the genuinely strong headline trial against that surrounding promotional inflation.

Bevisning, what actually backs this product

Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.

Strongest evidence tier
Tier 1Product RCT (peer-reviewed)
10 studies mapped
Tier 1Product RCT (peer-reviewed)
Promising Effects of Novel Supplement Formulas in Preventing Skin Aging in 3D Human Keratinocytes
Punzo A, Perillo M, Silla A, Malaguti M, Hrelia S, Barardo D, Caliceti C, Lorenzini A · 2024 · Nutrients, 16(16):2770 · In vitro concentrations approximating NOVOS Core/Vital ingredient ratios · Acute in vitro exposure protocol
NOVOS-affiliated ingredient combinations reduced chemotherapy-induced DNA strand breaks and oxidative damage in cultured skin cells.
This is a genuinely peer-reviewed paper (Nutrients, MDPI) with a NOVOS Labs employee as co-author, which is a real conflict of interest to disclose even though the journal itself is peer-reviewed. It is a cell-culture (in vitro) study, not a human or even animal study, so it speaks to plausible mechanism, not to real-world skin benefits from swallowing the product.
Tier 2Product RCT (not peer-reviewed)
STAMINA: Effects of a supplement to target ageing mechanisms on vascular function
Heiss C (senior author) et al., University of Surrey · 2026 · Manuscript posted as a preprint on SSRN; formal peer review reported as ongoing as of NOVOS's mars 5, 2026 update · n=61 · 15 g/day NOVOS Core (full commercial serving), vs. matched placebo · 6 months, with acute measurements 1–2 hours after first dose
Statistically significant between-group improvements vs. placebo in flow-mediated dilation (endothelial function, ~+2.9% to +3.9% adjusted difference), pulse wave velocity (arterial stiffness, ~-1.18 m/s adjusted difference), and systolic blood pressure (~-6.1 mmHg adjusted difference); no significant change in cholesterol or diastolic blood pressure.
This is the strongest single piece of product-specific evidence in this entire product category: an actual randomized, dubbelblind, placebokontrollerad trial on the exact commercial formula and dose. However, it is not yet peer-reviewed or published in an indexed journal — it exists as an SSRN preprint and a company press release, and outcome interpretation (e.g., comparing effect sizes to HIIT or Mediterranean diets) comes from NOVOS's own framing rather than the trial's statistical analysis plan. It is a real RCT, not a marketing fabrication, but it should be treated as provisional until it clears peer review.
Tier 3Ingredient RCT (matching dose)
Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes
Bannai M, Kawai N · 2007 · Sleep and Biological Rhythms · 3 g glycine before bedtime · Single-night and repeated-dose protocols
Improved subjective sleep quality and favorable shifts in polysomnography versus placebo.
NOVOS Core's 1,000 mg glycine dose is roughly one-third of the isolated 3 g dose used in this and related Japanese sleep studies, so calling this 'matching dose' evidence would overstate it; we classify it as Tier 3 only in the sense that it is a genuine human RCT on the same ingredient, while flagging the dose gap explicitly.
Tier 3Ingredient RCT (matching dose)
Analysis of Säkerhet from a Human Clinical Trial with Pterostilbene
Riche DM et al. · 2013 · Evidence-Based Complementary and Alternative Medicine (related dataset also published as Riche 2014 in the same journal) · n=80 · 50 mg twice daily (100 mg/day) or 125 mg twice daily (250 mg/day) pterostilbene vs. placebo · 6–8 weeks
Confirmed safety at doses up to 250 mg/day; the companion metabolic-parameters analysis reported blood pressure reductions, though a separate 2019 correspondence (Riche, Clin Nutr) noted pterostilbene modestly raised LDL cholesterol in this same trial population.
NOVOS Core's 50 mg pterostilbene dose matches the lower-dose arm of this trial, making it a legitimate dose-matched Tier 3 citation. Worth noting for balance: the same trial population showed an LDL-raising signal in follow-up correspondence, a nuance not mentioned in NOVOS's marketing.
Tier 3Ingredient RCT (matching dose)
Improved Oral Absorption of Quercetin from Quercetin Phytosome, a New Delivery System Based on Food Grade Lecithin
Riva A et al. · 2018 · European Tidskrift of Drug Metabolism and Pharmacokinetics · Quercetin Phytosome vs. unformulated quercetin, matched quercetin content · Single-dose pharmacokinetic comparison
Substantially improved plasma absorption of quercetin when delivered as a phytosome/lecithin complex versus plain quercetin powder.
Relevant to the broader quercetin-phytosome ingredient category used across the longevity-supplement industry; however, NOVOS Core's current publicly documented formula (per its own ingredients page) does not appear to list a standalone quercetin phytosome ingredient — fisetin is the flavonoid used instead. Included here for category completeness and comparison purposes, and flagged under unverified/formulation-history since we could not confirm quercetin phytosome is currently in NOVOS Core.
Tier 4Ingredient RCT (different dose)
Comparable anti-ageing efficacies of a multi-ingredient nutraceutical and a senolytic intervention in old mice
Brookes C, Fielder E, Low E, Barardo D, von Zglinicki T, Miwa S · 2024 · bioRxiv preprint (DOI 10.1101/2024.10.11.617853), version 3; no peer-reviewed journal publication located as of this review · n=38 · Daily NOVOS Core dietary supplementation (product-equivalent dose) vs. a senolytic drug combination (navitoclax + BAM15) vs. untreated controls · From 20 months to 30 months of age (10 months)
Median lifespan increased by roughly 18-20% in the NOVOS Core group versus untreated controls, a magnitude statistically comparable to the senolytic-drug positive control; frailty and cognitive measures trended favorably but did not all reach statistical significance.
This is a real, methodologically serious mouse study run by an independent academic lab (Newcastle University's Biosciences Institute, led by Thomas von Zglinicki and Satomi Miwa, with a co-author from NOVOS Labs). It remains an unpublished bioRxiv preprint as of this review — we found no evidence it has cleared peer review or appeared in a journal. Mouse lifespan extension, even at 18-20%, does not reliably predict human lifespan or healthspan effects, and NOVOS's own product page includes this caveat in fine print even while headlining the number.
Tier 4Ingredient RCT (different dose)
Rejuvant, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging
Demidenko O et al. · 2021 · Aging (Albany NY), 13(22):24485-24499 · n=42 · ~2 g/day Ca-AKG in a proprietary delayed-release form (a different product/formulation than NOVOS Core's Ca-AKG) · Average of 7 months of use
Average 8-year reduction in DNA-methylation-based biological age (TruAge test) in a retrospective, uncontrolled cohort.
This positive AKG data comes from a different company's delayed-release Ca-AKG formulation (Ponce De Leon Health's Rejuvant), not from NOVOS Core, and used roughly 4x the AKG dose NOVOS includes. A related 2026 Aging Cell study reportedly found this same delayed-release Rejuvant formulation outperformed dozens of other supplements (including standard AKG and NAD+ boosters) on biological-age correlation in a large observational cohort — again, not on NOVOS Core specifically. We classify this as Tier 4 (different dose/different product form) rather than direct product evidence.
Tier 5Mechanistic / animal / marketing
Six-month observational epigenetic aging pace study in NOVOS Core + Boost users
NOVOS Labs internal research team · 2022 · Not published in a peer-reviewed journal; reported directly on NOVOS's own website · n=12 · 1 sachet NOVOS Core + 2 capsules NOVOS Boost (250 mg NMN) daily · 6 months
Average DunedinPACE (pace-of-aging epigenetic clock) score fell by 6.1% across the group, with no formal placebo arm.
No control group, no blinding, tiny sample (n=12, one dropout), and conducted/analyzed entirely in-house by the company selling the product. Epigenetic clocks like DunedinPACE are themselves investigational research tools, not validated aging biomarkers accepted by regulators. This is presented prominently by NOVOS but amounts to a small internal case series, not clinical evidence.
Tier 5Mechanistic / animal / marketing
"950+ studies" backing NOVOS formulas
NOVOS Labs (marketing copy) · 2026 · Not a study — an aggregate citation count across NOVOS's marketing pages
NOVOS states its ingredients are collectively supported by more than 950 published studies (an earlier version of the same page cites 435 papers for Core + Boost specifically), spanning cell, animal, and human research across all 12 ingredients.
Classic Tier 5 language: a headline number built by summing loosely related ingredient literature (much of it in vitro or animal) rather than pointing to a specific study that tested the finished product at its labeled doses. A large study count for an ingredient like Vitamin C or magnesium says nothing about whether NOVOS Core's specific sub-clinical dose of that ingredient does anything. Treat this figure as promotional, not evidentiary.
Tier 5Mechanistic / animal / marketing
Fisetin is a senotherapeutic that extends health and lifespan
Yousefzadeh MJ et al. (Mayo Clinic / Scripps) · 2018 · EBioMedicine · Intermittent high-dose fisetin (not directly comparable to a 150 mg/day oral human dose) · Intermittent dosing protocol over the mouse lifespan
Fisetin reduced senescent cell markers and modestly extended lifespan/healthspan in mice; identified as the most potent senolytic among 10 flavonoids screened.
This landmark fisetin paper — the one most longevity brands cite, including NOVOS — is mouse and in vitro work, not a human trial. The related human senolytic work led by the Mayo Clinic/Kirkland-Pignolo group (ClinicalTrials.gov NCT04313634 and related fisetin frailty studies) exists but has reported mixed and still-preliminary results in small elderly cohorts; we found no completed, published, unambiguously positive human fisetin RCT that would justify NOVOS Core's 150 mg fisetin dose as clinically validated in people.

Claim check, vendor claims vs. our reading of the evidence

Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.

Supported
“NOVOS Core is 'one of the few longevity formulations ever evaluated in randomized, placebokontrollerad human clinical research'”
This specific claim is accurate and is the main reason NOVOS Core stands out in this category: the STAMINA trial (NCT06145087) is a real randomized, dubbelblind, placebokontrollerad trial on the exact commercial 15 g/day formula, which most competing all-in-one longevity blends simply do not have.
Not supported
“NOVOS Core's cardiovascular effects are 'comparable to' or 'exceed' effect sizes from HIIT, Mediterranean/DASH diets, and major weight loss”
These are indirect, informal cross-study comparisons made by NOVOS itself, not a head-to-head trial against exercise or diet interventions. Comparing effect sizes across entirely different study populations, methodologies, and endpoints is not a scientifically valid way to claim equivalence, even when the underlying trial data is real.
Not supported
“Formulas are 'backed by 950+ studies'”
This is an aggregate count of loosely related ingredient literature (much of it cell or animal research on doses that don't match the product), not evidence that the finished product or its specific low doses of each ingredient produce the claimed effects. Classic Tier 5 marketing language.
Partial support
“NOVOS Core extends lifespan (implied via the '18% longer lifespan in mice' headline)”
The underlying mouse study is real and was run by an independent, reputable academic lab, but it remains an unpublished bioRxiv preprint, and mouse lifespan results do not reliably translate to human lifespan extension — a caveat NOVOS does include in small print on its own product page even while leading with the headline number.
Not supported
“81% of customers notice meaningful improvements in skin, mood, energy, or sleep within two weeks”
This figure comes from an unblinded post-purchase customer survey, not a controlled study; expectation and placebo effects are not accounted for, and no comparator group exists.
Not supported
“NOVOS Core reduces cellular senescence in vitro by an amount comparable to rapamycin”
This is a cell-culture (in vitro) comparison, not a comparison of oral supplementation to rapamycin's clinical/animal effects; in vitro potency does not establish that an oral 15 g/day powder dose achieves comparable exposure in living tissue.

Regelverk status

Rules change often. We record when we last verified each row. See the full regulatory timeline →

US
Legal as supplement
All labeled NOVOS Core ingredients (Ca-AKG, fisetin, pterostilbene, glucosamine sulfate, glycine, magnesium malate, L-theanine, Rhodiola, ginger extract, hyaluronic acid, vitamin C, microdosed lithium) are conventional dietary ingredients under DSHEA; none are subject to the NMN-style drug-preclusion dispute that has affected NOVOS Boost.
Senast verifierad 2026-08-05
EU
Mixed Novel Food Review
Most Core ingredients are established EU food ingredients, but fisetin and Ca-AKG in supplement form have uneven Novel Food catalog status by member state, and enforcement varies; the product is sold into the EU primarily via direct international shipping from novoslabs.com rather than through an EU-registered listing we could verify.
Senast verifierad 2026-08-05
UK
Legal With Uncertainty On Some Actives
Sold openly to UK customers via direct shipping; individual actives like fisetin and Ca-AKG are not on the UK FSA's clearly-authorized list, creating the same ambiguity seen with many boutique longevity actives post-Brexit, though we found no evidence of enforcement action against NOVOS Core specifically.
Senast verifierad 2026-08-05
CA
Unclear Npn Status
We could not confirm a Health Canada Natural Product Number (NPN) specifically for NOVOS Core as a finished multi-ingredient product; some individual actives (e.g., branded fisetin extracts from other suppliers) have received NPNs in Canada, but that does not extend automatically to NOVOS's formulation.
Senast verifierad 2026-08-05

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

  • Exact current milligram dose of Vitamin C in NOVOS Core (not disclosed in the sources we could access).
  • The precise chemical form and milligram dose of the 'micro-dosed lithium' ingredient.
  • Whether NOVOS Core currently contains quercetin phytosome, NMN, or taurine — older third-party trackers and outdated internal notes listed these, but the current official NOVOS ingredients page we fetched (2026) lists a 12-ingredient formula without NMN, taurine, or quercetin, suggesting a formulation change since those older summaries were written. Treat any older claim that Core contains NMN or taurine as outdated.
  • A single, complete, publicly posted potency/purity CoA covering all 12 actives per batch (only microbial-safety CoAs and older, non-current heavy-metal/NMN-specific lab reports were confirmed).
  • Whether the STAMINA trial (SSRN preprint) has since cleared peer review and been published in an indexed journal after our review date.
  • Whether the Newcastle University mouse lifespan study has been accepted for peer-reviewed publication beyond its bioRxiv preprint status.
  • Formal Health Canada NPN status for NOVOS Core as a finished product.
Important to know
NMNAbsorption varies wildly by form. Sublingual and liposomal claim better uptake but human head-to-head data is limited.
Lithium (microdose)Orotate form has no comparative pharmacology data. Do not combine with prescription lithium or use with kidney disease. The ecological fallacy is real: water-lithium regions differ in many ways.
FisetinStandard capsules have <5% absorption. Look for liposomal or with piperine.
PterostilbeneHigh-dose pterostilbene can raise LDL. Keep to <150 mg/day unless working with a clinician.
GlucosamineThe hydrochloride form has weaker evidence. Often paired with chondroitin, which adds little. Shellfish-derived sources matter if you are allergic.
L-TheanineVery safe. Suntheanine® is the branded form with the most published data.
MagnesiumMagnesium oxide has ~4% absorption and mostly acts as a laxative. Always check the salt form, not just 'magnesium'.
GlycineNone major. Very sweet in powder form, mix in water or coffee.
Hyaluronic AcidMW matters for absorption; look for <10 kDa marketing.
Ca-AKGLong-term human safety data is essentially absent. Biological-age tests used in marketing are proxies, not proof of slowed aging.
Rhodiola RoseaCan be stimulating; take earlier in day.
GingerExtracts vary enormously in gingerol content — check for standardization. Mild heartburn at higher doses.

Redaktionellt notes

12 ingredients targeting 12 hallmarks of aging. Individual doses smaller than a mono-ingredient product.

In plain language

Why this scored this way

This NOVOS Labs NOVOS Core scores 6.1, making it below the site average. It delivers the full 340mg trial dose of Magnesium with grade A evidence (strong human trial data). At $5.93/day it's among the more expensive options in All-in-one.

What drives the score up

  • Dose-evidence score of 6.0 shows decent alignment with trial doses.
  • Tested by independent lab (transparency 7.5).
  • Community score of 8.0 with positive consumer feedback.
  • Magnesium is dosed at the full research level with grade A evidence (strong human trial data).
  • Hyaluronic Acid is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).

What drags it down

  • Fisetin (150mg is 30% of the 500mg trial dose) is significantly under-dosed.
  • Glucosamine (500mg is 33% of the 1500mg trial dose) is significantly under-dosed.
  • Glycine (1000mg is 33% of the 3000mg trial dose) is significantly under-dosed.
  • No public analysintyg available for independent verification.
  • At $5.93/day it's on the expensive side.

Why you'd choose it

  • You want Magnesium from a NOVOS Labs product.
  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You need a full trial dose of fisetin (this product under-doses it).
  • You want a cheaper option (this is $5.93/day).
Go deeper

Where this sits

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of NOVOS Core and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
Same shelf

Similar produkter

All All-in-one →

The next highest-scoring produkter in All-in-one, same scoring method, same rules.

Same maker

Other produkter from NOVOS Labs

Varumärke profile →