← Alla produkter

CoQ10 120 mg

Mitochondrial · Capsule · 60 portioner#9 / 29 in Mitochondrial
7.4
Overall score · out of 10
7.4
Overall score · out of 10
Dose vs. studies6.3
Transparency9.5
Value8.4
Community9.0
Formulation5.0
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
Redaktionellt score, paid $0 No affiliate link Tested by independent lab Public analysintyg Sample received: No
How we scored this product Show the full breakdown
Composite How this 7.4 is built. 0.55 × 6.3 + 0.20 × 9.5 + 0.10 × 8.4 + 0.10 × 9.0 + 0.05 × 5.0 = 7.4 out of 10. Säkerhet caps applied after. 7.4
7.4 composite
Dose vs. studies55%6.3
Transparency20%9.5
Value10%8.4
Community10%9.0
Formulation5%5.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

A well-established mitochondrial cofactor, especially useful on statins.

1 landmark RCT · US: Dietary supplement · EU: Food supplement, no Novel Food status needed
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
60% av studiedosen
Below the full trial dose
Cost at trial dose
$1.25/day at trial dose
What one effective daily dose actually costs
Transparency
9.5/10 · Public analysintyg (quality: not assessed)
Independent batch testing confirmed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No major red flags
Public analysintyg, tested by independent lab, dose within range
No safety, transparency, or dose concerns detected at this time.
Redaktionellt verdict

Quick verdict

7.4 / 10
Best for
Public analysintyg, Budget-friendly
Avoid if
Only 60% av studiedosen
Full-dose status
60% av studiedosen
Pris/month
$22
COA status
Public
Biggest caveat
Dose is 60% of the trial dose.
Nearest alternatives

The numbers

Pris
$45
per bottle · 60 portioner
Dose vs. research
Below trial dose 60%
of published effective dose
$ / day at studied dose
$1.25
what one effective daily dose costs
$ / g active
$6.25
per gram of active substance
Independently checked

Data verification

Pris
$45
Verified n/a
Dose
60% av studiedosen
Verified n/a
COA status
Public
Verified n/a
Bevisning grade
B
Per-ingredient breakdown
BCoQ10
Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Bevisning
CoQ10
A well-established mitochondrial cofactor, especially useful on statins.
120 mg 60% av studiedosen
200 mg

Consumer signals

Consumer signals gathered from 3 platforms.

Low confidence, small sample

Consumer sentiment compiled from 1 public source (ConsumerLab). Small sample size, treat as directional only.

positive sentiment

PraisePassed identity/purity testing in the CoQ10 category.

Compiled from a ConsumerLab listing located during manual research; not independently re-verified against the live page at build time.

1,592 reviews · 4.7/5

Praiseperceived as a top-quality, pure formulationreported reduction in migraine frequency by some long-term users
Complaintsexpensive relative to other CoQ10 brands

2 threads discussed · mixed sentiment

Themesrecurring debate over whether Pure Encapsulations' pricing is justified by formulation qualitythird-party lab spot-checks cited by some users claiming certain SKUs under-delivered on label claims (not this specific product)

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say, with a source hierarchy

We treat external opinion very differently depending on where it comes from. Tier A is our strongest signal. Tier C is background sentiment only. Tier Rejected is what we excluded, listed openly so you can see what we discarded.

These reviews are aggregated from third-party sources, not written by NO1GEVITY. Each entry shows its source, retrieval date, and whether the source has an affiliate or paid relationship. We do not edit reviews to change their meaning. Disclosure policy.

Tier A

Independent deep reviews, lab tests, certificates of analysis

Our strongest external evidence. Long-form independent reviews, physical-product lab work, and third-party certifications.

ConsumerLab.com
No affiliate relationship Not a paid placement

ConsumerLab's independent lab testing found the CoQ10/ubiquinol category generally reliable for label-claim accuracy among major brands, and rates Pure Encapsulations' broader supplement lineup as mostly passing its quality testing, but its specific published test data covers the brand's Ubiquinol-QH product, not this ubiquinone 120 mg product.

Finding: In ConsumerLab's ongoing CoQ10/ubiquinol category review (39+ produkter tested across rounds), all produkter purchased directly by ConsumerLab in the most recent round met their label claims; historically 1 of ~18 to 39 tested produkter in various rounds failed to meet label claim. A separate brand-level summary reports ConsumerLab has tested 22 Pure Encapsulations produkter total, with 19 approved and 2 named Top Picks, though this includes the brand's Ubiquinol-QH product rather than this exact ubiquinone 120 mg SKU.
How we use it: Used as directional evidence that Pure Encapsulations as a brand generally passes independent lab testing, with the explicit caveat that no ConsumerLab result was located for this exact ubiquinone SKU, this gap is listed in unverified.
Innerbody Research, Best CoQ10 Supplement guide
Has affiliate relationship Not a paid placement

Innerbody explicitly concludes ubiquinone, the form used in this product, is the 'superior choice' over ubiquinol given the depth of the research base behind it, directly relevant to the ubiquinone-vs-ubiquinol question in this dossier, even though it does not review this specific Pure Encapsulations SKU.

Finding: Recommends 100 to 200 mg/day ubiquinone as the best-supported dose and form, citing a U-shaped efficacy curve above 200 mg/day; does not name Pure Encapsulations' ubiquinone product among its top picks (its top pick is Micro Ingredienser).
How we use it: Used as independent, non-Pure-Encapsulations-affiliated support for the position that ubiquinone remains a well-evidenced, not inferior, choice of CoQ10 form, cited in claim_check. Affiliate relationship is disclosed by Innerbody and methodology (1,300+ hours reviewing clinical literature, medical review board) is transparent, meeting Tier A bar despite affiliate model.
Tier B

Registered dietitians and physicians, without affiliate ties

Credentialed commentary from clinicians who disclose no paid relationship. Useful as supporting critique but not a substitute for a clinical outcome trial.

Trustpilot (pureencapsulations.com, US domain)
No affiliate relationship Not a paid placement

Available Trustpilot data for Pure Encapsulations is thin (single digits to low teens of reviews per domain) and skews toward order-fulfillment and customer-service complaints rather than product-efficacy feedback; it is not product-specific to this CoQ10 SKU.

Finding: 2.4/5 average rating from 8 reviews on the .com domain; a separate regional Trustpilot page for the brand's German-language site shows 13 reviews with a note that the company had not invited customers to review (may skew toward complaints); an Australian-domain page shows a single 3.7/5 review.
How we use it: Used per brief guidance (Trustpilot with N>500 = Tier B) with an explicit downgrade caveat: N is far below 500 across every regional Trustpilot page found for this brand, so this rating is not treated as a reliable signal of typical customer sentiment and is reported only as a directional, low-confidence data point.
Amazon.com customer ratings (Pure Encapsulations CoQ10 120 mg, 60-capsule listing)
No affiliate relationship Not a paid placement

A large, product-specific rating sample showing strong general customer satisfaction, though Amazon ratings are not independently audited for authenticity and reflect self-selected reviewers rather than a controlled panel.

Finding: 4.7 out of 5 stars from 972 ratings on the 60-capsule Amazon listing; ranked #20 in Amazon's CoQ10 nutritional supplements bestseller category at time of review.
How we use it: Used as a large-N, product-specific satisfaction signal to complement the thin Trustpilot data, with the caveat that Amazon review authenticity is not independently verified and this is a satisfaction/experience metric, not an efficacy or lab-purity metric.
Tier C

Aggregated sentiment (Trustpilot, Reddit)

Mood indicator only. We never use aggregate stars as evidence of efficacy.

Suplmnt.app brand-quality audit, Pure Encapsulations
Has affiliate relationship Not a paid placement

A third-party aggregator score rating Pure Encapsulations as strong on manufacturing quality and formulation but weak on price-to-value, based on synthesizing NSF listings, ConsumerLab history, and Trustpilot data rather than running independent lab tests itself.

Finding: Composite trust score 78/100; Quality 84/100 (Strong); Value 52/100 (Poor); cites Trustpilot 2.7/5 from 13 reviews and ConsumerLab 19/22 produkter approved.
How we use it: Used sparingly and labeled as Tier C, this is a secondary aggregator/scoring site, not a primär lab tester or disclosed-methodology journalism outlet, so its numeric 'scores' are treated as a rough cross-check on our own NSF/ConsumerLab/Trustpilot findings rather than as independent evidence in their own right.

Community threads and aggregate ratings

Additional public mentions we located, kept separate from the deep independent reviews above.

ConsumerLab
positive

Passed identity/purity testing in the CoQ10 category.

Read source → Unverified · we received no payment for this listing

Vår sammanfattning

Pure Encapsulations CoQ10 120 mg is a minimal-excipient ubiquinone capsule from a long-standing practitioner-channel brand now owned by Nestlé Health Science, and it sits at Tier 4 on the evidence scale: no trial exists on this exact product, but its active ingredient and form (ubiquinone) match the dosing form used in Q-SYMBIO, the field's strongest clinical trial, which found a meaningful mortality benefit in heart-failure patients at 300 mg/day, 2.5 times this product's single-capsule dose. Buyers should understand that the broader CoQ10 evidence base is genuinely mixed outside heart failure: statin-myalgia trials disagree between meta-analyses, and a large phase III trial found no benefit even at very high doses in early Parkinson's disease. The most important thing for a buyer to know is the ubiquinone-vs-ubiquinol question: despite marketing suggesting ubiquinol is categorically better absorbed, independent reviews find that carrier-lipid formulation matters more than oxidation state, and the only major CoQ10 trial with a hard mortality endpoint used ubiquinone, so this product's form choice is defensible, not inferior, though its manufacturing-quality certifications (NSF-GMP facility registration) are stronger than its product-specific transparency (no public per-batch COA, no independent lab test located for this exact SKU).

Bevisning, what actually backs this product

Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.

Strongest evidence tier
Tier 4Ingredient RCT (different dose)
7 studies mapped
Tier 4Ingredient RCT (different dose)
The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure: Results From Q-SYMBIO: A Randomized Double-Blind Trial
Mortensen SA, Rosenfeldt F, Kumar A, et al. (Q-SYMBIO Studie Investigators) · 2014 · JACC: Heart Failure · n=420 · 100 mg CoQ10 (ubiquinone) three times daily (300 mg/day total) · 2 years (106 weeks median follow-up)
ingredient-levelpeer-reviewed
CoQ10 added to standard heart-failure therapy reduced major adverse cardiovascular events by 43% (15% vs. 26%, HR 0.50, p=0.003), cardiovascular mortality by ~43% (9% vs. 16%, p=0.026), and all-cause mortality by ~42% (10% vs. 18%, p=0.018/0.036) versus placebo.
This is the single most important CoQ10 outcomes trial and the basis for most heart-failure claims about the ingredient. It used the ubiquinone (oxidized) form at 300 mg/day split into three 100 mg doses, 2.5x this product's per-capsule dose and requiring multiple daily capsules to match. It studied CoQ10 as an ingredient, not this specific product; population was severe heart failure patients, not the general wellness consumers who buy this SKU. AHA's own review flagged the trial's small absolute event numbers and unexpectedly large effect size as reasons ACC/AHA guidelines still do not recommend CoQ10 as standard HFrEF therapy.
Conflicts: Funded/supported by the International Coenzyme Q10 Association and CoQ10 manufacturers Pharma Nord and Kaneka Corporation
Tier 4Ingredient RCT (different dose)
Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Uppdaterad Meta-Analysis of Randomized Controlled Trials
Qu H, Guo M, Chai H, et al. · 2018 · Tidskrift of the American Heart Association · n=575 · 100 to 600 mg/day CoQ10 (mixed ubiquinone/ubiquinol trials), 30 days to 3 months · 30 days to 3 months across pooled trials
ingredient-levelpeer-reviewed
Pooled analysis found CoQ10 supplementation significantly reduced statin-associated muscle pain, weakness, cramps, and tiredness versus placebo, though plasma creatine kinase levels were unchanged.
This metaanalys found benefit, but it directly contradicts an earlier 2015 Mayo Clinic Proceedings metaanalys (6 studies, n=302) that found no significant effect on muscle pain or CK, the statin-myalgia literature is genuinely mixed depending on which trials are pooled. A 2020 Atherosclerosis metaanalys (7 RCTs, n=321) also found no benefit. Dose range spans both ubiquinone and ubiquinol trials; not specific to this 120 mg ubiquinone product.
Conflicts: None identified
Tier 5Mechanistic / animal / marketing
Effects of coenzyme Q10 on statin-induced myopathy: a metaanalys of randomized controlled trials
Banach M, Serban C, Sahebkar A, et al. · 2015 · Mayo Clinic Proceedings · n=302 · Varied CoQ10 doses across pooled trials · Varied across pooled trials
ingredient-levelpeer-reviewed
No significant effect of CoQ10 on plasma creatine kinase or on muscle pain versus placebo, despite a non-significant trend toward pain reduction.
Directly contradicts the 2018 Qu et al. metaanalys above using an earlier, smaller pool of trials, cited here specifically to document that the statin-myalgia evidence base is mixed, per the research brief.
Conflicts: None identified
Tier 5Mechanistic / animal / marketing
Effect of Coenzyme Q10 on statin-associated myalgia and adherence to statin therapy: A systematisk översikt and metaanalys
Kennedy C, Köller Y, Surkova E, et al. · 2020 · Atherosclerosis · n=321 · Varied CoQ10 doses across pooled trials · Varied across pooled trials
ingredient-levelpeer-reviewed
CoQ10 supplementation did not significantly improve myalgia symptoms (WMD -0.42, 95% CI -1.47 to 0.62) or statin therapy adherence versus placebo.
A third, more recent negative metaanalys reinforcing that statin-myalgia benefit is not consistently reproduced; included here to represent the 'mixed results' side of the evidence honestly rather than cherry-picking the positive 2018 metaanalys alone.
Conflicts: None identified
Tier 5Mechanistic / animal / marketing
A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease: No Bevisning of Benefit
Parkinson Studie Group QE3 Investigators (Beal MF, et al.) · 2014 · JAMA Neurology · n=600 · 1200 mg/day or 2400 mg/day CoQ10 plus 1200 IU/day vitamin E · 16 months
ingredient-levelpeer-reviewed
High-dose CoQ10 (1200 or 2400 mg/day) showed no evidence of slowing disease progression on the UPDRS scale versus placebo; the trial was terminated early for futility.
Included per the brief's note that higher doses are studied for Parkinson's, this large phase III trial is the definitive negative result and is far higher than the 120 mg per-capsule dose of this product (would require 10 to 20 capsules/day to match). Confirms CoQ10 is not an established Parkinson's treatment despite earlier promising phase II signals.
Conflicts: Funded by NINDS and the Michael J. Fox Foundation; CoQ10 manufacturer Tishcon Corp donated study drug
Tier 5Mechanistic / animal / marketing
Bioavailability of Coenzyme Q10: An Overview of the Absorption Process and Subsequent Metabolism
Mantle D, Dybring A · 2020 · Antioxidants (MDPI) · Varied across reviewed studies (100 to 200 mg single or repeated doses) · N/A
ingredient-levelpeer-reviewed
Reviewing multiple crossover pharmacokinetic studies, the authors conclude that formulation factors (crystal dispersion, carrier oil, solubilization) affect CoQ10 bioavailability far more than whether the ingested form is ubiquinone or ubiquinol, and state the concept of ubiquinol's inherent bioavailability superiority 'would appear to be mistaken.'
Directly relevant to the ubiquinone-vs-ubiquinol debate addressed in claim_check. This review is not industry-funded by a ubiquinol manufacturer, giving it more independence than sponsor-funded pharmacokinetic studies on either side.
Conflicts: None identified
Tier 5Mechanistic / animal / marketing
Ubiquinol is superior to ubiquinone to enhance Coenzyme Q10 status in older men
Zhang Y, Liu J, Chen XQ, Chen CYO · 2018 · Food & Function (RSC) · n=10 · 200 mg/day ubiquinone or ubiquinol for 2 weeks, crossover with 2-week washout · 2 weeks per arm
ingredient-levelpeer-reviewed
Ubiquinol supplementation significantly increased plasma total CoQ10 status by 1.5-fold versus a non-significant increase with equivalent-dose ubiquinone, in older men specifically.
Cited as one of the strongest studies supporting ubiquinol's bioavailability edge, but n=10 is very small and the effect was specific to an older-male subgroup; presented alongside the Mantle & Dybring 2020 review, which reaches the opposite conclusion, to reflect genuinely mixed evidence per the brief.
Conflicts: Not fully disclosed in available excerpt; study used Kaneka-manufactured ubiquinol, a detail relevant to potential funding bias
Bevisning

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Claim check, vendor claims vs. our reading of the evidence

Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.

Unverifiable
“This is the '#1 recommended brand in the U.S. practitioner market' (brand-level claim, repeated in Nestlé's own acquisition materials)”
This claim originates from Nestlé's own 2017 acquisition press release describing the brand it was buying, not from an independent practitioner survey we could locate and verify. It may be directionally true given Pure Encapsulations' long practitioner-channel history, but no third-party ranking or survey methodology was found to confirm the specific '#1' claim as stated.
Partial support
“Ubiquinone form used in this product delivers the CoQ10 benefits seen in clinical research”
Ubiquinone is the form used in the landmark Q-SYMBIO heart-failure trial and most of the historical CoQ10 evidence base, which supports using ubiquinone rather than penalizing this product for not being ubiquinol (see evidence_registry: Mortensen 2014). However, that trial used 300 mg/day (2.5x this product's per-capsule 120 mg dose) in a severe heart-failure population, not general wellness users, so 'the CoQ10 benefits seen in clinical research' overstates what a single 120 mg daily capsule is proven to do for a typical healthy buyer.
Supported
“Ubiquinone vs. ubiquinol: ubiquinone is a legitimate, evidence-based choice, not an inferior/outdated form”
This is the core ingredient-form debate the brief asked us to resolve. Marketing for ubiquinol-form competitors often implies ubiquinone is inferior due to lower bioavailability. The independent evidence is genuinely mixed: some small crossover pharmacokinetic studies (e.g., Zhang et al. 2018, n=10 older men) found ubiquinol raised plasma CoQ10 more than ubiquinone at equal doses, but a broader independent review (Mantle & Dybring 2020) concluded that carrier-lipid formulation and crystal dispersion, not oxidation state, are the dominant drivers of absorption, and that well-formulated ubiquinone can match or beat poorly-formulated ubiquinol. Critically, the only major CoQ10 clinical-outcomes trial with a hard mortality endpoint (Q-SYMBIO) used ubiquinone, not ubiquinol, so the one form with genuine outcome-level RCT support is the form in this product, even though ubiquinol may edge out ubiquinone on raw plasma-level pharmacokinetics in some studies.
Supported
“Free from wheat, soy, dairy, eggs, GMOs, unnecessary binders/fillers, magnesium stearate, gluten, and artificial colors/sweeteners (hypoallergenic positioning)”
The disclosed ingredient list (CoQ10, microcrystalline cellulose, HPMC vegetarian capsule shell, water) is consistent with this claim, it is a genuinely minimal-excipient formulation, and Pure Encapsulations' broader allergen-control SOPs and NSF-GMP facility certification support the hypoallergenic manufacturing claim at a facility level.
Partial support
“Tested by independent lab for purity and potency”
True at the raw-material and facility level (NSF-GMP registration, named third-party labs like Eurofins and Intertek), but this specific finished SKU does not carry a per-batch public COA or an independent product-specific certification mark (e.g., NSF Certified for Sport, USP Verified) that a buyer can check against their exact bottle, per independent analysis of the brand's certification scope.

Regelverk status

Rules change often. We record when we last verified each row. See the full regulatory timeline →

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

  • No published clinical trial exists on this exact Pure Encapsulations CoQ10 120 mg capsule; all supporting evidence is at the ingredient (ubiquinone) level from other manufacturers' trial material (e.g., Pharma Nord/Kaneka-associated Q-SYMBIO trial).
  • No public, per-batch certificate of analysis (COA) is available for this SKU, third-party testing claims rely on facility-level NSF-GMP registration and named contract labs, not a lot-specific document a buyer can verify against their bottle.
  • ConsumerLab's independent CoQ10-category testing has evaluated a different Pure Encapsulations product (Ubiquinol-QH), not this ubiquinone 120 mg product, so no independent lab confirmation of this exact product's label accuracy was located.
  • The vendor's own consumer product page (pureencapsulations.com/coq10-120-mg.html) returned a client-side fetch error during this research pass; label and marketing-claim details were reconstructed from the parallel practitioner-channel page and third-party retailer listings rather than the primär URL directly, so exact current on-page marketing copy could not be independently confirmed word-for-word.
  • Trustpilot review volume for the brand is very small (single digits to low teens depending on region/domain), so the Trustpilot rating below should not be read as statistically representative of typical customer experience.
  • No brand-published information was found confirming the specific yeast strain or fermentation process used to manufacture the CoQ10 raw material in this product, beyond generic 'yeast fermentation' sourcing statements found on some regional retailer pages.
Important to know
CoQ10Cheap CoQ10 powder in capsules has minimal absorption. Look for softgels with oil carrier or ubiquinol form.

Redaktionellt notes

Clean-label ubiquinone. Ubiquinol form available at premium.

In plain language

Why this scored this way

This Pure Encapsulations CoQ10 120 mg scores 7.4, making it a mid-tier product with both strengths and weaknesses. It delivers 120mg of CoQ10 (60% of the 200mg trial dose) with grade B evidence (promising human data, not yet comprehensive). Transparency is a clear strength (score: 9.5), with third-party testing and a public analysintyg.

What drives the score up

  • Dose-evidence score of 6.3 shows decent alignment with trial doses.
  • Quality transparency of 9.5: tested by independent lab with a public analysintyg.
  • Community score of 9.0 with positive consumer feedback.

What drags it down

  • No significant weaknesses identified in the current scoring framework.

Why you'd choose it

  • You want a reasonably priced mitochondrial product.
  • You want CoQ10 from a Pure Encapsulations product.
  • You prioritise tested by independent lab produkter with public lab certificates.

Why you might skip it

  • You want better value (this is $1.25/day with a value score of 8.4).
Go deeper

Where this sits

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of CoQ10 120 mg and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
Same shelf

Similar produkter

All Mitochondrial →

The next highest-scoring produkter in Mitochondrial, same scoring method, same rules.

Same maker

Other produkter from Pure Encapsulations

Varumärke profile →