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Senolytique (Liposomal Quercetin, Fisetin, Spermidin)

Autophagy · Capsule · 60 portioner#20 / 22 in Autophagy
4.9
Overall score · out of 10
4.9
Overall score · out of 10
Dose vs. studies4.3
Transparency7.0
Value3.0
Community6.0
Formulation5.0
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
Redaktionellt score, paid $0 No affiliate link Tested by independent lab No public analysintyg Sample received: No
How we scored this product Show the full breakdown
Composite How this 4.9 is built. 0.55 × 4.3 + 0.20 × 7.0 + 0.10 × 3.0 + 0.10 × 6.0 + 0.05 × 5.0 = 4.9 out of 10. Säkerhet caps applied after. 4.9
4.9 composite
Dose vs. studies55%4.3
Transparency20%7.0
Value10%3.0
Community10%6.0
Formulation5%5.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Best-studied 'senolytic' ingredient, though evidence is early.

4 landmark RCTs · US: Dietary supplement · EU: Food supplement (extract-dependent)

Highly-hyped senolytic; the strong evidence is in mice, not people.

3 landmark RCTs · US: Dietary supplement · EU: Food supplement

The autophagy-inducing polyamine with promising cognitive data.

3 landmark RCTs · US: Dietary supplement · EU: Novel Food status for concentrates >7 mg; wheat-germ traditional food
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
15% av studiedosen
Well below the trial dose
Cost at trial dose
$5.62/day at trial dose
What one effective daily dose actually costs
Transparency
7.0/10 · No public analysintyg
Independent batch testing confirmed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public analysintyg
Certificate of Analysis not published
Without a public analysintyg, batch purity and potency cannot be independently verified.
Underdosed
Dose at 15% av studiedosen
Below 50% of the dose used in published clinical trials.
Buyer complaints
Trustpilot: Australia Post delivery issues
Recurring themes from consumer review platforms.
Redaktionellt verdict

Quick verdict

4.9 / 10
Best for
Budget-friendly
Avoid if
Only 15% av studiedosen, No public analysintyg
Full-dose status
15% av studiedosen
Pris/month
$26
COA status
Not public
Biggest caveat
Dose is 15% of the trial dose.
Nearest alternatives

The numbers

Pris
$52
per bottle · 60 portioner
Dose vs. research
Below trial dose 15%
of published effective dose
$ / day at studied dose
$5.62
what one effective daily dose costs
$ / g active
$7.53
per gram of active substance
Independently checked

Data verification

Pris
$52
Verified n/a
Dose
15% av studiedosen
Verified n/a
COA status
Not public
Verified n/a
Bevisning grade
BCB
Per-ingredient breakdown
BQuercetin
CFisetin
BSpermidin
Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Bevisning
77.0 mg 15% av studiedosen
500 mg
35.0 mg 7% av studiedosen
500 mg
Spermidin
The autophagy-inducing polyamine with promising cognitive data.
3.0 mg 250% av studiedosen
1.2 mg

Consumer signals

Consumer signals gathered from 2 platforms.

Medium confidence

1 threads discussed · positive sentiment

Praisepersonal positive experience reported over time
ThemesA Reddit user's ongoing account of taking Renue by Science Senolytique reports a positive experience with the combination senolytic formula.

Compiled from a Reddit discussion thread listing located during research; verified at build time.

mixed sentiment

Praiseexcellent product qualitytesting results available on website
ComplaintsAustralia Post delivery issues
ThemesThe Australian Trustpilot listing for Renue by Science praises product quality and available third-party test results, though delivery via Australia Post drew complaints.

Compiled from a Trustpilot listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Important to know
QuercetinPlain quercetin dihydrate has poor absorption. Phytosome forms deliver 10 to 20× more into blood.
FisetinStandard capsules have <5% absorption. Look for liposomal or with piperine.
SpermidinProduct labels often say 'wheat germ extract 800 mg', that could be 0.8 mg or 8 mg of actual spermidine. Insist on labeled spermidine content.

Redaktionellt notes

A genuinely liposomal 3-in-1 combo, but each ingredient is present at a fraction of its individual standalone Renue product's dose and well below senolytic trial doses (e.g. Mayo Clinic fisetin trials use ~20mg/kg intermittently), best understood as a maintenance-dose antioxidant blend rather than a senolytic protocol.

In plain language

Why this scored this way

This Renue By Science Senolytique (Liposomal Quercetin, Fisetin, Spermidin) scores 4.9, making it among the lowest-scoring produkter we track. It delivers the full 3.0mg trial dose of Spermidin with grade B evidence (promising human data, not yet comprehensive). At $5.62/day it's among the more expensive options in Autophagy.

What drives the score up

  • Tested by independent lab (transparency 7.0).
  • Spermidin is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).

What drags it down

  • Dose-evidence score of 4.3 is below average for the site.
  • Overall dose is only 15% of the trial dose across ingredients.
  • Quercetin (77.0mg is 15% of the 500mg trial dose) is significantly under-dosed.
  • Fisetin (35.0mg is 7% of the 500mg trial dose) is significantly under-dosed.
  • Spermidin (3.0mg is 250% of the 1.2mg trial dose) is well above the trial dose. More is not always better.

Why you'd choose it

  • You want Spermidin from a Renue By Science product.
  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You need a full trial dose of quercetin (this product under-doses it).
  • You want a standard dose of spermidine (this product is well above it).
Go deeper

Where this sits

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of Senolytique (Liposomal Quercetin, Fisetin, Spermidin) and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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