Collagen Plus

Collagen Peptider Grade B

Collagen Plus

Name: Collagen Plus
Brand: Thorne HealthTech
SKU: thorne-collagen-plus
Price: 63.0 USD
Availability: InStock
Rating: 3.4 (357 reviews)

Connective tissue · Powder · 30 portioner#7 / 18 in Connective tissue

6.9

Overall score · out of 10

6.9

Overall score · out of 10

Dose vs. studies7.0

Transparency7.0

Value7.8

Community6.0

Formulation5.0

Tier 4

Ingredient RCT (different dose)

The ingredient was tested in an RCT but at a different dose, or only in animals.

Redaktionellt score, paid $0 No affiliate link Tested by independent lab No public analysintyg Sample received: No

How we scored this product Show the full breakdown

Dose vs. studies (55%) 7.0

Transparency (20%) 7.0

Value (10%) 7.8

Community sentiment (10%) 6.0

Formulation (5%) 5.0

Composite 6.9

6.9 composite

Dose vs. studies55%7.0

Transparency20%7.0

Value10%7.8

Community10%6.0

Formulation5%5.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Genuine benefits for skin and joint tissue at 10 g/day.

1 landmark RCT · US: Dietary supplement · EU: Food supplement

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research

130% av studiedosen

Meets or exceeds the published effective dose

Cost at trial dose

$1.62/day at trial dose

What one effective daily dose actually costs

Transparency

7.0/10 · No public analysintyg

Independent batch testing confirmed

Consumer signals

357 reviews across platforms · 3.4/5 · medium confidence

Operational signal only, never used as clinical evidence

Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public analysintyg

Certificate of Analysis not published

Without a public analysintyg, batch purity and potency cannot be independently verified.

Buyer complaints

Trustpilot: poor customer service; Trustpilot: shipping delays

Recurring themes from consumer review platforms.

Best for

Full trial dose

Avoid if

No public analysintyg

Full-dose status

Meets trial dose

Pris/month

$63

COA status

Not public

Biggest caveat

No public Certificate of Analysis.

Nearest alternatives

Vital Proteins Advanced Collagen Peptider + Creatine Vital Proteins · Poäng 7.7
Hydrolysed Collagen Peptider DoNotAge · Poäng 7.5
Collagen Peptider Powder (Hydrolyzed Bovine Collagen) BulkSupplements · Poäng 7.4

The numbers

Pris

$63

per bottle · 30 portioner

Dose vs. research

Above trial dose 130%

of published effective dose

$ / day at studied dose

$1.62

what one effective daily dose costs

$ / g active

$0.16

per gram of active substance

Independently checked

Data verification

Pris

$63

Verified n/a

Dose

130% av studiedosen

Verified n/a

COA status

Not public

Verified n/a

Bevisning grade

Per-ingredient breakdown

BCollagen Peptider

Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient

Dose in this product

Trial dose

Bevisning

Collagen Peptider

Genuine benefits for skin and joint tissue at 10 g/day.

Choi et al. 2019

13000.0 mg 130% av studiedosen

10000 mg

3.2 /5

High confidence

386 reviews across 4 platforms (4 sources)

Source diversity: 92%

AmazonRedditTrustpilotiHerb

Praiseproduct quality generally trustedsupports skin, hair, and joint health

Complaintspoor customer serviceshipping delays

Last checked: 2026-08-07

Consumer signals

3.4 out of 5 across 357 verified reviews on 4 platforms.

Medium confidence

Consumer sentiment compiled from 4 public sources.

Trustpilot

29 reviews · 1.8/5 · negative sentiment

Praiseproduct quality generally trusted

Complaintspoor customer serviceshipping delays

ThemesThorne's brand-level Trustpilot score is poor, driven mainly by customer-service and shipping complaints rather than product efficacy.

Compiled from Trustpilot listing located during research; verified at build time.

Amazon

357 reviews · 4.3/5 · mixed sentiment

Praisesupports skin, hair, and joint health

Complaintsstrong, cough-syrup-like flavor

ThemesBuyers like the collagen content and health benefits but frequently criticize the flavor.

Compiled from Amazon listing located during research; verified at build time.

iHerb

positive sentiment

Praiseeasy to mixgood taste in flavored version

ThemesiHerb reviewers of the flavored Passion Berry variant report a pleasant taste and easy mixing.

Compiled from iHerb listing located during research; verified at build time.

2 threads discussed · mixed sentiment

Praisetrusted for third-party testing

Complaintslower collagen dose (13g) vs. competitors like Vital Proteins (20g)

ThemesReddit users compare Thorne's lower per-serving collagen dose unfavorably to competitors like Vital Proteins.

Compiled from Reddit listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

Independent external anchors

Public sources on this same product, unrelated to NO1GEVITY. NIH DSLD is the US government's registered label database (shown verbatim). SuppCo.com is a separate, unaffiliated commercial site with no partnership or data-sharing arrangement with us. NO1GEVITY scores are computed independently of both.

Unaffiliated third-party site

SuppCo.com

SuppCo is a separate, unaffiliated supplement-tracking site with no partnership, data-sharing agreement, or business relationship with NO1GEVITY. We are not endorsed by them and they do not endorse us. The two facts below are individually verified against the manufacturer or NSF; the outbound link is provided only so readers can independently cross-check on a third-party site if they want to.

Tested by independent lab, Yes

NIH DSLD registered label

DSLD ID 280413, UPC 6 93749 01311 2

Portionstorlek16.5 Gram(s) (One Scoop)

Portioner per container30

Supplement Facts panel, verbatim

Calories61 Calorie(s)

Total Carbohydrates2 Gram(s)1% DV

Protein12 mg

Sodium65 mg3% DV

Collagen Peptider13 Gram(s)

MitoHeal500 mg

Nicotinamide Riboside Hydrogen Malate125 mg

Betaine Anhydrous50 mg

HydroPeach20 mg

What others say, with a source hierarchy

We treat external opinion very differently depending on where it comes from. Tier A is our strongest signal. Tier C is background sentiment only. Tier Rejected is what we excluded, listed openly so you can see what we discarded.

These reviews are aggregated from third-party sources, not written by NO1GEVITY. Each entry shows its source, retrieval date, and whether the source has an affiliate or paid relationship. We do not edit reviews to change their meaning. Disclosure policy.

Tier A

Independent deep reviews, lab tests, certificates of analysis

Our strongest external evidence. Long-form independent reviews, physical-product lab work, and third-party certifications.

Examine.com, Collagen page

No affiliate relationship Not a paid placement

Independent, ingredient-level corroboration that the collagen-skin evidence base, while not empty, carries meaningful caveats consistent with this dossier's funding-bias finding.

Finding: Examine's evidence summary for collagen and skin outcomes generally describes the evidence as moderate but notes substantial heterogeneity and funding-related concerns across the underlying trial literature.

How we use it: Used as independent ingredient-category corroboration of the funding-bias caveat central to this dossier's claim_check.

Tier B

Registered dietitians and physicians, without affiliate ties

Credentialed commentary from clinicians who disclose no paid relationship. Useful as supporting critique but not a substitute for a clinical outcome trial.

Trustpilot (thorne.com aggregate)

No affiliate relationship Not a paid placement

General brand reputation signal, not product- or claim-specific.

Finding: Thorne's aggregate Trustpilot rating (brand-wide, not product-specific) is generally favorable, though this reflects overall brand/customer-service sentiment rather than efficacy feedback on this specific Collagen Plus SKU.

How we use it: Used only as brand-level customer-service context, not as evidence of this product's efficacy.

Tier C

Aggregated sentiment (Trustpilot, Reddit)

Mood indicator only. We never use aggregate stars as evidence of efficacy.

Reddit r/SkincareAddiction and r/Supplements consensus threads on collagen supplements

No affiliate relationship Not a paid placement

Informal but directionally consistent with this dossier's funding-bias-adjusted skepticism about strong skin-aging claims for oral collagen.

Finding: Community sentiment on oral collagen supplements for skin is mixed-to-skeptical, with many contributors citing the modest and contested nature of the clinical evidence and noting that topical retinoids have a stronger independent evidence base for visible skin-aging outcomes than oral collagen.

How we use it: Used only as low-confidence directional color, explicitly labeled Tier C.

Vår sammanfattning

Thorne Collagen Plus combines a substantial 13 g bovine collagen peptide dose with four additional actives, nicotinamide riboside, betaine anhydrous, a branded ceramide extract, and an undisclosed-ratio proprietary redcurrant/blackcurrant blend, none of which have been tested together as a combination in any published trial. The product's central marketing premise, that oral collagen supports skin elasticity and a youthful appearance, rests on genuinely contested evidence: while an earlier, larger metaanalys found positive pooled effects, a more recent 2025 analysis that specifically excluded industry-funded studies found no significant skin benefit, with positive results concentrated in company-funded and lower-quality trials, a material finding this dossier flags as central to an honest assessment of this product category, not unique to this brand. A further 2026 re-analysis found that wrinkle- and skin-density-specific claims were statistically fragile, driven by outlier studies, while hydration and elasticity effects held up somewhat better. The nicotinamide riboside component is dosed well below the amount used in the one relevant skin-adjacent RCT located (a psoriasis-inflammation trial at 8x this product's dose), and this dossier explicitly documents that a separate, frequently-conflated skin-cancer-prevention trial (ONTRAC) tested a different compound, plain nicotinamide, not nicotinamide riboside, and must not be cited in support of this ingredient. The undisclosed internal ratio of the proprietary berry-extract blend further limits independent verification of that component's dosing rationale.

Bevisning, what actually backs this product

Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.

Strongest evidence tier

Tier 4Ingredient RCT (different dose)

5 studies mapped

Tier 0No source

IMPORTANT MARKETING-CONFUSION FLAG: Nicotinamide (vitamin B3 amide) skin-cancer prevention trial, frequently conflated with nicotinamide riboside

Chen AC, Martin AJ, Choy B, et al. (ONTRAC trial) · 2015 · New England Tidskrift of Medicine · n=386 · 500 mg nicotinamide (vitamin B3 amide, a DIFFERENT compound from the nicotinamide riboside in this product) twice daily · 12 months

ingredient-levelpeer-reviewed

Oral nicotinamide reduced the rate of new non-melanoma skin cancers by 23% versus placebo.

EXPLICITLY FLAGGED: this landmark trial tested plain nicotinamide (also called niacinamide), a different molecule from the nicotinamide riboside (NR) in this Thorne product, despite the similar names. Marketing materials across the supplement industry sometimes blur this distinction; this dossier documents it here specifically to prevent the ONTRAC trial's skin-cancer-prevention result from being misattributed to this product's NR ingredient, which has not been tested for this indication.

Conflicts: Funded by the Australian National Health and Medical Research Council and other public research bodies

Tier 4Ingredient RCT (different dose)

Effects of oral collagen peptide supplementation on skin health: systematisk översikt and metaanalys considering funding source

Multiple authors (2025 metaanalys) · 2025 · Peer-reviewed dermatology/nutrition journal (indexed in PubMed) · n=1474 · Varied collagen peptide doses across pooled trials (this product provides 13,000 mg/13 g per portion, within the typical studied range of 2.5-15 g/day) · Varied across pooled trials (typically 8-12 weeks)

ingredient-levelpeer-reviewed

When restricting the analysis to studies NOT funded by pharmaceutical/supplement companies, there was no statistically significant effect of collagen supplementation on skin aging outcomes; positive effects were concentrated in company-funded and lower-quality studies.

This is the single most important and sobering finding for this product category: when the funding-bias lens is applied, the evidence for collagen-for-skin claims, the core marketing premise of this product, largely disappears. This is ingredient-level evidence (not specific to Thorne's formulation, which is a 13 g bovine collagen dose within the typically studied range), but it directly undercuts the confidence a buyer should place in skin-related collagen marketing claims generally, including this product's.

Conflicts: This is itself a metaanalys explicitly designed to isolate and test for funding-source bias in the underlying primary-trial literature

Tier 5Mechanistic / animal / marketing

Oral collagen supplementation for skin aging: a systematisk översikt and metaanalys

Multiple authors · 2023 · Peer-reviewed (PMC-indexed) · n=1721 · Varied collagen doses across pooled trials · Varied, typically 8-24 weeks

ingredient-levelpeer-reviewed

Pooled analysis found statistically significant positive effects of oral collagen supplementation on skin hydration, elasticity, and wrinkles versus control/placebo.

This earlier, larger pooled review found positive effects without stratifying for funding source, directly contrasting with the 2025 funding-bias-adjusted analysis (PMID 40324552) above. Presenting both is necessary for an honest picture: the raw pooled literature looks favorable, but when industry-funded studies are excluded, the effect weakens substantially or disappears, a genuinely contested area, not settled science in either direction.

Conflicts: Not stratified by funding source in this particular review

Tier 5Mechanistic / animal / marketing

Wrinkle and skin-density outcomes in collagen peptide RCTs: outlier-sensitivity re-analysis

Multiple authors (2026 re-analysis) · 2026 · Peer-reviewed (PMC-indexed) · n=2534 · Varied collagen doses across pooled trials · Varied

ingredient-levelpeer-reviewed

Reported wrinkle-reduction and skin-density improvements in the pooled literature were found to be statistical artifacts driven by a small number of high-leverage outlier studies; only hydration, elasticity, and skin-barrier-function improvements remained robust after removing these outliers.

A methodologically important recent re-analysis suggesting that some of the more dramatic collagen-for-skin marketing claims (wrinkle reduction, skin density/thickness) rest on statistically fragile foundations, while more modest claims (hydration, elasticity) have a somewhat more robust evidence base.

Conflicts: Not disclosed in available excerpt

Tier 5Mechanistic / animal / marketing

Nicotinamide riboside effects on skin: no direct RCT located; adjacent inflammation trial

Multiple authors · 2024 · JCI Insight · n=27 · 500 mg nicotinamide riboside twice daily (1000 mg/day total, 8x this product's 125 mg per-serving dose) · 4 weeks

ingredient-levelpeer-reviewed

NR supplementation reduced Th17-driven skin inflammation markers in psoriasis patients.

This is a real RCT on nicotinamide riboside (the same compound in this product) affecting skin, but it studied an inflammatory skin disease endpoint (psoriasis-associated Th17 inflammation) at 8x this product's dose, not general cosmetic skin-aging outcomes, it cannot be used to support anti-aging or cosmetic skin claims for this product's 125 mg NR dose.

Conflicts: Not disclosed in available excerpt

Collagen Peptider Choi et al. 2019

Bevisning

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Claim check, vendor claims vs. our reading of the evidence

Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.

Misleading

“Supports skin elasticity, hydration, and a youthful appearance”

This is the most important finding in this dossier. While an earlier, larger pooled metaanalys (26 RCTs, n=1,721) found positive skin effects from collagen supplementation generally, a more recent 2025 metaanalys that explicitly isolated studies NOT funded by pharmaceutical/supplement companies found no statistically significant skin benefit, positive results were concentrated in industry-funded and lower-quality studies (PMID 40324552). A separate 2026 outlier-sensitivity re-analysis found that specific claims about wrinkle reduction and skin density were statistical artifacts driven by a few high-leverage studies, while only hydration and elasticity held up as more robust. Given this, broad 'youthful appearance' marketing language overstates what independent, funding-bias-adjusted evidence currently supports, even though this product's 13 g collagen dose is within the range used in the underlying trials.

Unsupported For Skin-Specific Claims; Partially Supported For General Nad+ Mechanism

“Nicotinamide riboside supports cellular energy and healthy aging”

NR's role as an NAD+ precursor is established biochemistry, and NAD+ decline with age is well documented, but no RCT was located testing NR specifically for skin or cosmetic aging outcomes at this product's 125 mg dose or any dose. A psoriasis-inflammation RCT used NR at 8x this dose (1000 mg/day) for a disease-specific endpoint, not cosmetic skin aging. Critically, this dossier flags that the well-known skin-cancer-prevention trial (ONTRAC, NEJM 2015) that some marketing conflates with NR actually tested plain nicotinamide, a different compound, and cannot be used to support this product's NR claims.

Unverifiable

“Formulated with a blend without listed amounts of redcurrant and blackcurrant extract (MitoHeal) at a clinically studied dose”

This ingredient is disclosed as a named blend without listed amounts with a total combined weight (500 mg) but no individual breakdown of redcurrant versus blackcurrant extract amounts, making it impossible to independently verify whether either component is present at a dose matching any specific published study, per the brief's requirement to flag blends without listed amounts explicitly.

Partial support

“Tested by independent lab for purity and potency”

Thorne's manufacturing facilities carry NSF registration at the facility level, but this dossier could not confirm this specific SKU carries an independently audited, product-specific certification mark (such as NSF Certified for Sport, which some other Thorne produkter do carry) or a public per-batch Certificate of Analysis.

Se alla in Connective tissue →

Regelverk status

Rules change often. We record when we last verified each row. See the full regulatory timeline →

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

The individual gram amounts of redcurrant extract versus blackcurrant extract within the 500 mg 'MitoHeal' blend without listed amounts are not disclosed on the label, preventing dose-matching against any specific published study on either ingredient alone.
Whether this exact product carries NSF Certified for Sport or any other independently audited, product-specific quality certification (as opposed to facility-level GMP registration) was not confirmed.
Whether the nicotinamide riboside in this formulation is licensed ChromaDex Niagen-brand NR (as several other Thorne NAD+ produkter are known to use) or an alternate NR supplier was not confirmed for this specific SKU.
No RCT was located testing this exact multi-ingredient combination (collagen + NR + betaine + ceramide + berry extract together) for any outcome, all supporting evidence is at the individual-ingredient level, and even that evidence for the core collagen-skin claim is contested once funding bias is accounted for.
The specific reason for this product's on-label pregnancy warning (which ingredient(s) drive it) was not confirmed from available vendor documentation.
Current EU novel-food authorization status for nicotinamide riboside specifically (as distinct from nicotinamide/niacinamide, which has long-established food status) was not verified for this product's EU retail listings.

Important to know

Collagen PeptiderAdding vitamin C boosts collagen synthesis. Cold water dissolves poorly, mix in warm liquid.

Redaktionellt notes

A skin-focused collagen powder that pairs 13g of collagen peptides with a dose of nicotinamide riboside, an unusual and notable combination since most collagen produkter don't include an NAD+ precursor; the NR dose itself is not disclosed clearly enough to compare against NiaCel.

In plain language

Why this scored this way

This Thorne HealthTech Collagen Plus scores 6.9, making it a mid-tier product with both strengths and weaknesses. It delivers the full 13000.0mg trial dose of Collagen Peptider with grade B evidence (promising human data, not yet comprehensive). At $1.62/day it's among the more expensive options in Connective tissue.

What drives the score up

Dose-evidence score of 7.0 shows decent alignment with trial doses.
Tested by independent lab (transparency 7.0).
Collagen Peptider is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).

What drags it down

No public analysintyg available for independent verification.
Limited consumer feedback (community score: 6.0).
At $1.62/day it's on the expensive side.

Why you'd choose it

You want Collagen Peptider from a Thorne HealthTech product.
You want a tested by independent lab product.
You want doses that align with published research.

Why you might skip it

You want a product with a publicly available CoA.
You want a cheaper option (this is $1.62/day).

Go deeper

Where this sits

Actives inside

Collagen Peptider

Kategori

Varumärke

Thorne HealthTech profile →

Jämför this product → Visit brand site →

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of Collagen Plus and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →

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