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CoQ10 (formerly Q-Best 100)

Mitochondrial · Softgel · 60 portioner#22 / 29 in Mitochondrial
6.7
Overall score · out of 10
6.7
Overall score · out of 10
Dose vs. studies6.3
Transparency7.0
Value8.0
Community6.0
Formulation8.0
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
Redaktionellt score, paid $0 No affiliate link Tested by independent lab No public analysintyg Sample received: No
How we scored this product Show the full breakdown
Composite How this 6.7 is built. 0.55 × 6.3 + 0.20 × 7.0 + 0.10 × 8.0 + 0.10 × 6.0 + 0.05 × 8.0 = 6.7 out of 10. Säkerhet caps applied after. 6.7
6.7 composite
Dose vs. studies55%6.3
Transparency20%7.0
Value10%8.0
Community10%6.0
Formulation5%8.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

A well-established mitochondrial cofactor, especially useful on statins.

1 landmark RCT · US: Dietary supplement · EU: Food supplement, no Novel Food status needed
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
50% av studiedosen
Below the full trial dose
Cost at trial dose
$1.53/day at trial dose
What one effective daily dose actually costs
Transparency
7.0/10 · No public analysintyg
Independent batch testing confirmed
Consumer signals
42 reviews across platforms · 3.8/5 · medium confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public analysintyg
Certificate of Analysis not published
Without a public analysintyg, batch purity and potency cannot be independently verified.
Buyer complaints
Trustpilot: unresponsive customer service; Trustpilot: shipping delays and order issues
Recurring themes from consumer review platforms.
Redaktionellt verdict

Quick verdict

6.7 / 10
Best for
Budget-friendly
Avoid if
Only 50% av studiedosen, No public analysintyg
Full-dose status
50% av studiedosen
Pris/month
$23
COA status
Not public
Biggest caveat
Dose is 50% of the trial dose.
Nearest alternatives

The numbers

Pris
$46
per bottle · 60 portioner
Dose vs. research
Below trial dose 50%
of published effective dose
$ / day at studied dose
$1.53
what one effective daily dose costs
$ / g active
$7.67
per gram of active substance
Independently checked

Data verification

Pris
$46
Verified n/a
Dose
50% av studiedosen
Verified n/a
COA status
Not public
Verified n/a
Bevisning grade
B
Per-ingredient breakdown
BCoQ10
Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Bevisning
CoQ10
A well-established mitochondrial cofactor, especially useful on statins.
100.0 mg 50% av studiedosen
200 mg
2.5 /5
Medium confidence Pris exceeds satisfaction
42 reviews across 4 platforms (4 sources)
Source diversity: 92%
AmazonRedditTrustpilotiHerb
Praisehelps ease heart palpitationshigh quality product
Complaintsunresponsive customer serviceshipping delays and order issues
Last checked: 2026-08-07

Consumer signals

3.8 out of 5 across 42 verified reviews on 4 platforms.

Medium confidence

Consumer sentiment compiled from 4 public sources.

42 reviews · 2.4/5 · negative sentiment

Complaintsunresponsive customer serviceshipping delays and order issues
ThemesThorne's brand-level Trustpilot rating remains poor, dominated by customer-service and shipping complaints.

Compiled from Trustpilot listing located during research; verified at build time.

positive sentiment

Praisehelps ease heart palpitationshigh quality product
ThemesAmazon reviewers report Thorne's CoQ10-containing formula helps with heart palpitations and is high quality.

Compiled from Amazon listing located during research; verified at build time.

positive sentiment

Praiseexceptional quality and absorptionhighly recommended
ThemesiHerb reviewers consistently rate this product's quality and absorption very highly.

Compiled from iHerb listing located during research; verified at build time.

4 threads discussed · positive sentiment

Praiserecommended for optimal absorption and third-party testingused in IVF protocols
Complaintsconsidered pricier than some alternatives
ThemesReddit users, including in IVF-focused communities, highly recommend Thorne's CoQ10 for its absorption and purity testing despite a higher price.

Compiled from Reddit listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

Independent external anchors

Public sources on this same product, unrelated to NO1GEVITY. NIH DSLD is the US government's registered label database (shown verbatim). SuppCo.com is a separate, unaffiliated commercial site with no partnership or data-sharing arrangement with us. NO1GEVITY scores are computed independently of both.

Unaffiliated third-party site
SuppCo.com

SuppCo is a separate, unaffiliated supplement-tracking site with no partnership, data-sharing agreement, or business relationship with NO1GEVITY. We are not endorsed by them and they do not endorse us. The two facts below are individually verified against the manufacturer or NSF; the outbound link is provided only so readers can independently cross-check on a third-party site if they want to.

NIH DSLD registered label
DSLD ID 182608, UPC 6 93749 62401 1
Portionstorlek1 Gelcap(s)
Portioner per containern/a
Supplement Facts panel, verbatim
Calories10 Calorie(s)
Total Fat1 Gram(s)1% DV
Protein0.5 Gram(s)1% DV
Coenzyme Q10100 mg

What others say (unverified)

No external reviews aggregated yet for this product.

Vår sammanfattning

Thorne's CoQ10 delivers a standard 100 mg ubiquinone dose with several lipophilic additives (flaxseed oil, lycopene, turmeric, CLA) marketed as absorption enhancers, though no dedicated trial tests that specific combination. The best outcomes evidence for ubiquinone CoQ10 (the Q-SYMBIO heart-failure trial) used three times this product's per-softgel dose in a severely ill population, and the widely repeated statin-myalgia benefit is contradicted by multiple independent meta-analyses. This is a competently formulated, standard-form CoQ10 product, but its 'optimally absorbed' positioning is a plausible, untested formulation choice rather than a proven bioavailability advantage.

Bevisning, what actually backs this product

Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.

Strongest evidence tier
Tier 4Ingredient RCT (different dose)
4 studies mapped
Tier 4Ingredient RCT (different dose)
The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure: Results From Q-SYMBIO: A Randomized Double-Blind Trial
Mortensen SA, Rosenfeldt F, Kumar A, et al. (Q-SYMBIO Studie Investigators) · 2014 · JACC: Heart Failure · n=420 · 100 mg CoQ10 (ubiquinone) three times daily (300 mg/day total) · 2 years (106 weeks median follow-up)
ingredient-levelpeer-reviewed
CoQ10 added to standard heart-failure therapy reduced major adverse cardiovascular events by 43% (15% vs. 26%, HR 0.50, p=0.003), cardiovascular mortality by ~43% (9% vs. 16%, p=0.026), and all-cause mortality by ~42% (10% vs. 18%, p=0.018/0.036) versus placebo.
The single most important CoQ10 outcomes trial, using the same ubiquinone (oxidized) form as Thorne's product but at 300 mg/day split into three 100 mg doses, 3x this product's per-softgel dose, requiring three softgels/day to match. Studied in severe heart-failure patients, not general wellness consumers; ACC/AHA guidelines still do not recommend CoQ10 as standard HFrEF therapy despite this result, citing small absolute event numbers.
Conflicts: Funded/supported by the International Coenzyme Q10 Association and CoQ10 manufacturers Pharma Nord and Kaneka Corporation
Tier 4Ingredient RCT (different dose)
Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Uppdaterad Meta-Analysis of Randomized Controlled Trials
Qu H, Guo M, Chai H, et al. · 2018 · Tidskrift of the American Heart Association · n=575 · 100-600 mg/day CoQ10 (mixed ubiquinone/ubiquinol trials), 30 days to 3 months · 30 days to 3 months across pooled trials
ingredient-levelpeer-reviewed
Pooled analysis found CoQ10 supplementation significantly reduced statin-associated muscle pain, weakness, cramps, and tiredness versus placebo, though plasma creatine kinase levels were unchanged.
Contradicts an earlier 2015 Mayo Clinic Proceedings metaanalys (6 studies, n=302) that found no significant effect, and a 2020 Atherosclerosis metaanalys (7 RCTs, n=321) that also found no benefit, the statin-myalgia literature is genuinely mixed. Not specific to this 100 mg ubiquinone product.
Conflicts: None identified
Tier 5Mechanistic / animal / marketing
Effects of coenzyme Q10 on statin-induced myopathy: a metaanalys of randomized controlled trials
Banach M, Serban C, Sahebkar A, et al. · 2015 · Mayo Clinic Proceedings · n=302 · Varied CoQ10 doses across pooled trials · Varied across pooled trials
ingredient-levelpeer-reviewed
No significant effect of CoQ10 on plasma creatine kinase or on muscle pain versus placebo, despite a non-significant trend toward pain reduction.
Cited to document the mixed statin-myalgia evidence base honestly, directly contradicting the 2018 Qu et al. metaanalys above.
Conflicts: None identified
Tier 5Mechanistic / animal / marketing
Bioavailability of Coenzyme Q10: An Overview of the Absorption Process and Subsequent Metabolism
Mantle D, Dybring A · 2020 · Antioxidants (MDPI) · Varied across reviewed studies (100-200 mg single or repeated doses) · N/A
ingredient-levelpeer-reviewed
Concludes that formulation factors (crystal dispersion, carrier oil, solubilization) affect CoQ10 bioavailability far more than whether the ingested form is ubiquinone or ubiquinol, stating the idea of ubiquinol's inherent superiority 'would appear to be mistaken.'
Directly relevant to Thorne's marketing angle, which emphasizes absorption enhancers (flaxseed oil, lycopene, CLA) rather than switching to ubiquinol, this review supports the general premise that delivery-vehicle formulation matters more than raw ubiquinone-vs-ubiquinol chemistry, though it doesn't test Thorne's specific additive combination.
Conflicts: None identified
Bevisning

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Claim check, vendor claims vs. our reading of the evidence

Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.

Unverifiable
“Optimally absorbed CoQ10 formulation via added flaxseed oil, lycopene, turmeric, and CLA”
There is a real, independent-review-supported premise that delivery-vehicle formulation (oil-based carriers, particle size) affects CoQ10 absorption more than the ubiquinone-vs-ubiquinol distinction (https://pmc.ncbi.nlm.nih.gov/articles/PMC7278738/). However, no dedicated pharmacokinetic study was located testing Thorne's specific combination of flaxseed oil, lycopene, turmeric, and CLA against a plain ubiquinone softgel, so the 'optimally absorbed' framing rests on a plausible but untested formulation choice, not a head-to-head bioavailability trial.
Partial support
“Standard ubiquinone form (as opposed to ubiquinol) is an adequate, effective CoQ10 form (implicit in Thorne's product choice; the company also does not sell a ubiquinol version under this name)”
Bevisning is genuinely split: a 2020 independent review concludes ubiquinol's presumed bioavailability superiority 'would appear to be mistaken' (https://pmc.ncbi.nlm.nih.gov/articles/PMC7278738/), while a small 2018 crossover RCT in older men (n=10) found ubiquinol raised plasma CoQ10 status 1.5-fold more than ubiquinone (https://pubs.rsc.org/en/content/getauthorversionpdf/c8fo00971f). Thorne's ubiquinone choice is defensible but not definitively superior or inferior based on current evidence.

Regelverk status

Rules change often. We record when we last verified each row. See the full regulatory timeline →

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

  • No dedicated bioavailability study was located testing Thorne's specific absorption-enhancer additive blend (flaxseed oil, lycopene, turmeric, CLA) against plain ubiquinone CoQ10.
  • No public per-batch Certificate of Analysis was located for this SKU despite Thorne's facility-level NSF certification.
  • No RCT was located using this exact branded product; all outcome evidence is at the ubiquinone-ingredient level, mostly at higher doses (300 mg/day) than this product's single-softgel dose (100 mg).
  • The statin-myalgia benefit claim commonly associated with CoQ10 is contradicted by at least two independent meta-analyses, a nuance not disclosed on Thorne's retail page.
Important to know
CoQ10Cheap CoQ10 powder in capsules has minimal absorption. Look for softgels with oil carrier or ubiquinol form.

Redaktionellt notes

Standard ubiquinone CoQ10 at a common 100mg dose; ubiquinol forms (e.g. competitors' Q10) generally absorb better in adults over 40, which this product does not use.

In plain language

Why this scored this way

This Thorne HealthTech CoQ10 (formerly Q-Best 100) scores 6.7, making it a mid-tier product with both strengths and weaknesses. It delivers 100.0mg of CoQ10 (50% of the 200mg trial dose) with grade B evidence (promising human data, not yet comprehensive). At $1.53/day it's among the more expensive options in Mitochondrial.

What drives the score up

  • Dose-evidence score of 6.3 shows decent alignment with trial doses.
  • Tested by independent lab (transparency 7.0).

What drags it down

  • No public analysintyg available for independent verification.
  • Limited consumer feedback (community score: 6.0).
  • At $1.53/day it's on the expensive side.

Why you'd choose it

  • You want a reasonably priced mitochondrial product.
  • You want CoQ10 from a Thorne HealthTech product.
  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You want a cheaper option (this is $1.53/day).
Go deeper

Where this sits

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of CoQ10 (formerly Q-Best 100) and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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