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NiaCel 400
How we scored this product Show the full breakdown
Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.
This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.
Question 1
Does the molecule work?
Does the molecule work?
The science behind each active ingredient, independent of which brand sells it.
A methyl donor added to NAD+ formulas as a supporting cofactor, not a headline active.
Question 2
Is this bottle good?
Is this bottle good?
The specific product: dose, price, transparency, and what buyers report.
Question 3
What's the catch?
What's the catch?
Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.
Quick verdict
The numbers
Data verification
Per-ingredient breakdown
All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.
What's inside
Consumer signals
Consumer signals gathered from 3 platforms.
Medium confidenceConsumer sentiment compiled from 3 public sources (ConsumerLab, Examine.com, Trustpilot).
positive sentiment
Compiled from a ConsumerLab listing located during manual research; not independently re-verified against the live page at build time.
positive sentiment
Compiled from a Examine.com listing located during manual research; not independently re-verified against the live page at build time.
4.5/5 · positive sentiment
Compiled from a Trustpilot listing located during manual research; not independently re-verified against the live page at build time.
These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.
Independent external anchors
Public sources on this same product, unrelated to NO1GEVITY. NIH DSLD is the US government's registered label database (shown verbatim). SuppCo.com is a separate, unaffiliated commercial site with no partnership or data-sharing arrangement with us. NO1GEVITY scores are computed independently of both.
What others say, with a source hierarchy
We treat external opinion very differently depending on where it comes from. Tier A is our strongest signal. Tier C is background sentiment only. Tier Rejected is what we excluded, listed openly so you can see what we discarded.
These reviews are aggregated from third-party sources, not written by NO1GEVITY. Each entry shows its source, retrieval date, and whether the source has an affiliate or paid relationship. We do not edit reviews to change their meaning. Disclosure policy.
Independent deep reviews, lab tests, certificates of analysis
Our strongest external evidence. Long-form independent reviews, physical-product lab work, and third-party certifications.
Names Thorne as category-leading on purity and third-party testing despite the operational Trustpilot score.
Aggregated sentiment (Trustpilot, Reddit)
Mood indicator only. We never use aggregate stars as evidence of efficacy.
Aggregate score 2.4 / 5. Complaints concentrate on delivery, billing, and customer service — not on product quality or purity.
Community threads and aggregate ratings
Additional public mentions we located, kept separate from the deep independent reviews above.
Passed ConsumerLab identity/purity testing in NAD+ precursor category.
Examine lists NR as one of the best-validated NAD+ boosters, with an established safety record.
Thorne brand-level 4.5/5. Cited for practitioner-grade quality.
Vår sammanfattning
Bevisning, what actually backs this product
Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.
Research behind this product
The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.
Claim check, vendor claims vs. our reading of the evidence
Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.
Regelverk status
Rules change often. We record when we last verified each row. See the full regulatory timeline →
What we could not verify
We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.
- The precise elemental NR content of the 415 mg NRHM dose on the current label — Thorne does not publish an elemental-NR conversion figure for this product.
- Whether NiaCel 400 (this specific NRHM formulation) has a confirmed EU Novel Food authorization independent of ChromaDex's NR-chloride filing.
- The exact methodology and full results of the 2025 ChromaDex brand-testing round referenced only via a secondary video source.
- Whether Thorne has a public, batch-specific, downloadable Certificate of Analysis for this exact SKU (the company describes internal testing but NO1GEVITY could not locate a public per-batch CoA on thorne.com for NiaCel 400).
-
Reddit r/Supplements community forumpositive sentiment
Community discussion exists and is predominantly positive, highlighting perceived benefits and lower cost compared with Tru Niagen. No single Reddit thread is treated as a representative product review.
no direct URLchecked 2026-08-07 -
Thorne on-site reviews own platform
The product page is a first-party page with customer-review presentation, but no product rating or count was extracted.
verified 2026-08-07Open source → -
Amazon customers aggregator
An Amazon listing for this exact product was located. The product URL is not retained because marketplace listings can change.
no direct URLchecked 2026-08-07
Redaktionellt notes
Best-price licensed Niagen® NR product on the market. NSF Certified for Sport.
Why this scored this way
This Thorne HealthTech NiaCel 400 scores 7.0, making it a mid-tier product with both strengths and weaknesses. It delivers the full 400mg trial dose of NR with grade B evidence (promising human data, not yet comprehensive). Transparency is a clear strength (score: 9.5), with third-party testing and a public analysintyg.
What drives the score up
- Quality transparency of 9.5: tested by independent lab with a public analysintyg.
- Community score of 9.0 with positive consumer feedback.
- NR is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).
What drags it down
- Dose-evidence score of 5.5 is below average for the site.
- Betaine (TMG) (25mg is 1% of the 3000mg trial dose) is significantly under-dosed.
Why you'd choose it
- You want a reasonably priced nad+ booster product.
- You want NR from a Thorne HealthTech product.
- You prioritise tested by independent lab produkter with public lab certificates.
Why you might skip it
- You need a full trial dose of betaine (this product under-doses it).
Where this sits
Spot an error?
If you are the manufacturer or brand owner of NiaCel 400 and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.
We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.
Request a correction →Similar produkter
All NAD+ booster →The next highest-scoring produkter in NAD+ booster, same scoring method, same rules.