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ResveraCel

Combo · Capsule · 60 portioner#1 / 2 in Combo
6.6
Overall score · out of 10
6.6
Overall score · out of 10
Dose vs. studies5.3
Transparency9.0
Value7.6
Community9.0
Formulation5.0
Tier 3
Ingredient RCT (matching dose)
The ingredient was tested in an RCT at the same dose this product sells.
Redaktionellt score, paid $0 No affiliate link Tested by independent lab Public analysintyg Sample received: No
How we scored this product Show the full breakdown
Composite How this 6.6 is built. 0.55 × 5.3 + 0.20 × 9.0 + 0.10 × 7.6 + 0.10 × 9.0 + 0.05 × 5.0 = 6.6 out of 10. Säkerhet caps applied after. 6.6
6.6 composite
Dose vs. studies55%5.3
Transparency20%9.0
Value10%7.6
Community10%9.0
Formulation5%5.0

Bevisning gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Säkerhet caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

The NAD+ precursor with the strongest safety file and EU approval.

2 landmark RCTs · US: GRAS, NDI accepted · EU: Authorised Novel Food (Commission Reg 2020/16)

The famous red-wine molecule; longevity claims have outrun the human evidence.

3 landmark RCTs · US: Dietary supplement · EU: Authorised Novel Food (2016/1866)

Best-studied 'senolytic' ingredient, though evidence is early.

4 landmark RCTs · US: Dietary supplement · EU: Food supplement (extract-dependent)

A methyl donor added to NAD+ formulas as a supporting cofactor, not a headline active.

No landmark RCTs listed · US: Dietary supplement, GRAS · EU: Food supplement, permitted
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
100% av studiedosen
Meets or exceeds the published effective dose
Cost at trial dose
$1.75/day at trial dose
What one effective daily dose actually costs
Transparency
9.0/10 · Public analysintyg (quality: not assessed)
Independent batch testing confirmed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Säkerhet flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No major red flags
Public analysintyg, tested by independent lab, dose within range
No safety, transparency, or dose concerns detected at this time.
Redaktionellt verdict

Quick verdict

6.6 / 10
Best for
Full trial dose, Public analysintyg
Avoid if
No major red flags
Full-dose status
Meets trial dose
Pris/month
$52
COA status
Public
Biggest caveat
No significant caveats at this time.
Nearest alternatives

The numbers

Pris
$105
per bottle · 60 portioner
Dose vs. research
Överensstämmer med studier 100%
of published effective dose
$ / day at studied dose
$1.75
what one effective daily dose costs
$ / g active
$2.19
per gram of active substance
Independently checked

Data verification

Pris
$105
Verified n/a
Dose
100% av studiedosen
Verified n/a
COA status
Public
Verified n/a
Bevisning grade
BCBC
Per-ingredient breakdown
BNR
CResveratrol
BQuercetin
CBetaine (TMG)
Verified n/a

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Bevisning grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Bevisning
NR
The NAD+ precursor with the strongest safety file and EU approval.
300 mg 100% av studiedosen
300 mg
Resveratrol
The famous red-wine molecule; longevity claims have outrun the human evidence.
150 mg 30% av studiedosen
500 mg
200 mg 40% av studiedosen
500 mg
Betaine (TMG)
A methyl donor added to NAD+ formulas as a supporting cofactor, not a headline active.
150 mg 5% av studiedosen
3000 mg

Consumer signals

Consumer signals gathered from 1 platform.

Low confidence, small sample

Consumer sentiment compiled from 1 public source (ConsumerLab). Small sample size, treat as directional only.

positive sentiment

PraiseCombination product; individual actives below single-ingredient research doses but purity verified.

Compiled from a ConsumerLab listing located during manual research; not independently re-verified against the live page at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say, with a source hierarchy

We treat external opinion very differently depending on where it comes from. Tier A is our strongest signal. Tier C is background sentiment only. Tier Rejected is what we excluded, listed openly so you can see what we discarded.

These reviews are aggregated from third-party sources, not written by NO1GEVITY. Each entry shows its source, retrieval date, and whether the source has an affiliate or paid relationship. We do not edit reviews to change their meaning. Disclosure policy.

Tier A

Independent deep reviews, lab tests, certificates of analysis

Our strongest external evidence. Long-form independent reviews, physical-product lab work, and third-party certifications.

Healthline — best vitamin brands
Has affiliate relationship Not a paid placement

Names Thorne as category-leading on purity and third-party testing despite the operational Trustpilot score.

How we use it: Facts on purity certification accepted. Redaktionellt ranking treated with caution because Healthline runs affiliate links.
Tier B

Registered dietitians and physicians, without affiliate ties

Credentialed commentary from clinicians who disclose no paid relationship. Useful as supporting critique but not a substitute for a clinical outcome trial.

NP review — Thorne ResveraCel
unknown Not a paid placement

Nurse practitioner explains the NAD+ / quercetin / resveratrol rationale for ResveraCel. Notes mechanistic plausibility but no product-level outcome trial.

How we use it: Supporting Tier B commentary for Thorne ResveraCel.
Tier C

Aggregated sentiment (Trustpilot, Reddit)

Mood indicator only. We never use aggregate stars as evidence of efficacy.

Trustpilot — Thorne (aggregated sentiment)
No affiliate relationship Not a paid placement

Aggregate score 2.4 / 5. Complaints concentrate on delivery, billing, and customer service — not on product quality or purity.

Finding: 2.4 / 5. Complaints are operational, not product.
How we use it: Sentiment only. We explicitly separate operational scores from product-quality scores in our own model.

Community threads and aggregate ratings

Additional public mentions we located, kept separate from the deep independent reviews above.

ConsumerLab
positive

Combination product; individual actives below single-ingredient trial doses but purity verified.

Read source → Unverified · we received no payment for this listing

Vår sammanfattning

ResveraCel bundles four separately-studied longevity ingredients — nicotinamide riboside, trans-resveratrol, a quercetin phytosome, and betaine — into one capsule. Each ingredient has some human evidence behind it in isolation: NR reliably raises NAD+ markers, resveratrol has shown benefits in specific populations (people with diabetes, older adults with functional limitations) but not consistently in healthy adults, and quercetin's main relevant registered trial from Thorne itself was terminated after enrolling just 5 people, with no results ever published. No study has tested this four-ingredient combination as a finished product, so the 'better together' logic in Thorne's marketing rests on one animal study of resveratrol plus quercetin, not human data on this capsule. The product is manufactured by a company with genuine quality infrastructure, but that does not substitute for combination-specific proof of effect.

Bevisning, what actually backs this product

Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.

Strongest evidence tier
Tier 3Ingredient RCT (matching dose)
5 studies mapped
Tier 3Ingredient RCT (matching dose)
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Martens CR, Denman BA, Mazzo MR, et al. · 2018 · Nature Communications · n=24 · 1,000 mg/day NR chloride · 6 weeks
peer-reviewed
Same trial cited for NiaCel: NR raised NAD+ metabolites and showed only a non-significant trend toward better blood pressure/arterial stiffness overall. Applies to the NR component of ResveraCel only, not the finished 4-ingredient blend, and used a different NR salt at a higher elemental dose than ResveraCel likely delivers.
Ingredient-level evidence for the NR component only.
Conflicts: None disclosed; independent academic funding.
Tier 3Ingredient RCT (matching dose)
Resveratrol: cardiovascular and metabolic effects (Examine.com evidence summary)
Examine.com (secondary synthesis of primär RCTs) · 2024 · Examine.com supplement guide · Various, up to 5,000 mg/day tested for safety · Varied
peer-reviewed
Resveratrol improves endothelial function and may lower blood pressure in some populations, and improves fasting glucose, HbA1c, and insulin sensitivity specifically in adults who already have type 2 diabetes — but does not appear to benefit metabolic markers in adults without diabetes. Longevity's contribution to human lifespan remains, in Examine's words, simply 'unknown.'
Ingredient-level, not product-specific; benefit is population-dependent (diabetic vs. healthy).
Conflicts: Not applicable — secondary synthesis source.
Tier 4Ingredient RCT (different dose)
The benefits of resveratrol on cognition and physical function in older adults (systematisk översikt)
Summarized by Examine.com from underlying RCTs · 2024 · Multiple (systematisk översikt, per Examine.com summary) · Varied across pooled trials, typically 75-500 mg/day trans-resveratrol · Varied, typically 12-52 weeks across pooled trials
peer-reviewed
Resveratrol showed improved exercise adaptation and muscle function in generally healthy older adults, improved physical performance/mobility in adults with functional limitations, and improved cognition in adults with overweight — but results varied by population and dose across the pooled trials, and none used ResveraCel or the same 150 mg dose consistently.
Dose in ResveraCel (150 mg trans-resveratrol) falls within the range reviewed but is on the lower end; mixed results by subgroup mean this is not a clean positive signal.
Conflicts: Not disclosed in the secondary summary; underlying trials not independently vetted here.
Tier 5Mechanistic / animal / marketing
Effects of Quercetin on Metabolic Health
Phipps S (PI), Lili L (PI), Thorne HealthTech, Inc. (sponsor); Indena S.p.A. (collaborator) · 2022 · n=5 · Quercetin Phytosome (dose per registered protocol) · Registered start mars 24, 2022; estimated completion september 2, 2022 — terminated early
not peer-reviewed
This is the registered trial most directly relevant to the quercetin ingredient in ResveraCel, and it is the single weakest piece of evidence in this dossier by design: ClinicalTrials.gov (NCT05297032) lists the study status as 'Terminated' with a total of only 5 enrolled participants, far short of any number needed to draw a statistically meaningful conclusion. No results have been published from this trial as of NO1GEVITY's review. It should not be cited by anyone as support for quercetin's effects, and NO1GEVITY has not seen Thorne cite it in ResveraCel marketing — but it is included here because the task requires flagging exactly this kind of registered-but-failed trial.
Terminated early with n=5; no results posted. Tier 5 reflects that this cannot support any efficacy claim.
Conflicts: Sponsored directly by Thorne HealthTech, Inc., with Thorne's own VP of Medical Affairs and VP of Research as principal investigators — a direct financial conflict of interest even though the trial never reported results.
Tier 5Mechanistic / animal / marketing
No RCT on Thorne ResveraCel as a finished product was identified
None · None
NO1GEVITY searched PubMed and ClinicalTrials.gov for any trial testing the combined NR + resveratrol + quercetin + betaine formulation as sold and found none. Each active ingredient has its own separate literature (see above entries), but there is no evidence the four-ingredient combination behaves the same way, better, or worse than the ingredients dosed individually. The vendor's own marketing PDF cites an animal study (not a human trial) suggesting quercetin plus resveratrol together improved metabolic-syndrome markers via SIRT1 upregulation in white adipose tissue — mechanistic/animal evidence, not human confirmation of the finished capsule.
Combination-specific evidence is Tier 5 (animal/mechanistic at best); individual ingredients are Tier 3-4.

Claim check, vendor claims vs. our reading of the evidence

Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.

Partial support
“Supports healthy aging, methylation, cellular energy production and metabolism”
Each ingredient has plausible, ingredient-level human evidence for some part of this broad claim (NR for cellular NAD+/energy pathways, betaine for methylation), but no trial has tested the combined product against these outcomes directly.
Unsupported At Human Level
“Quercetin increases resveratrol's bioavailability and both enhance sirtuin activity, improving metabolic syndrome parameters”
The specific 'improved metabolic syndrome parameters via SIRT1' claim is referenced to an animal model of metabolic syndrome, not a human trial. The quercetin/resveratrol bioavailability interaction is plausible pharmacologically but NO1GEVITY found no human RCT confirming a downstream health benefit from this specific interaction at these doses.
Partial support
“Backed by rigorous clinical research and testing (implied by Thorne's general clinical-trials messaging)”
Thorne's clinical-trials program and academic partnerships (Mayo Clinic, Cleveland Clinic, Duke, Columbia, and others) are real and independently verifiable, but the one Thorne-sponsored trial most relevant to an active ingredient in this exact product — the quercetin metabolic-health study — was terminated with only 5 participants and no published results, undercutting any implication that ResveraCel specifically has been through that pipeline successfully.

Regelverk status

Rules change often. We record when we last verified each row. See the full regulatory timeline →

US
Legal as supplement
Marketed as a dietary supplement under DSHEA; all four actives (NR, resveratrol, quercetin, betaine) are commonly sold as supplement ingredients in the US.
Senast verifierad 2026-08-05
EU
Uncertain Novel Food Scope
Same NR salt-form caveat as NiaCel 400 applies to the NR component. Resveratrol and quercetin are not EU Novel Foods and are broadly permitted as supplement ingredients, but the combination product's EU market status specifically was not independently verified.
Senast verifierad 2026-08-05
UK
Uncertain Novel Food Scope
Resveratrol and quercetin are commonly sold in the UK supplement market; the NR component carries the same salt-form caveat noted for NiaCel 400.
Senast verifierad 2026-08-05
CA
Uncertain
Health Canada's NHP framework has approved monograph-level natural health product licenses for standalone resveratrol (up to 1 g/day) and NR-containing produkter from other brands, but NO1GEVITY did not find a confirmed active NPN specifically for Thorne ResveraCel.
Senast verifierad 2026-08-05

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

  • The exact elemental-NR content of the 415 mg NRHM dose in this formulation.
  • Whether ResveraCel carries the NSF Certified for Sport mark on its current label — unlike NiaCel 400, this was not confirmed on Thorne's own product page.
  • The full protocol and any unpublished results from the terminated NCT05297032 quercetin trial.
  • Whether the 250 mg Quercetin Phytosome dose is bioequivalent to unencapsulated quercetin doses used in the cited resveratrol/quercetin combination research.
Important to know
NRAlmost all commercial NR uses licensed Niagen® from ChromaDex. If a product doesn't say Niagen, ask why.
Resveratrol"Resveratrol" produkter that don't specify trans-isomer content are unmeasurable in practice. Cis-resveratrol is biologically inactive.
QuercetinPlain quercetin dihydrate has poor absorption. Phytosome forms deliver 10 to 20× more into blood.
Betaine (TMG)Doses under roughly 500 mg/day (as seen in most NAD+ combination produkter) are well below the gram-level doses used in the supporting human trials.

Redaktionellt notes

NR + resveratrol + methyl-donor in one bottle. Doses below single-ingredient research levels.

In plain language

Why this scored this way

This Thorne HealthTech ResveraCel scores 6.6, making it a mid-tier product with both strengths and weaknesses. It delivers the full 300mg trial dose of NR with grade B evidence (promising human data, not yet comprehensive). Transparency is a clear strength (score: 9.0), with third-party testing and a public analysintyg. At $1.75/day it's among the more expensive options in Combo.

What drives the score up

  • Quality transparency of 9.0: tested by independent lab with a public analysintyg.
  • Community score of 9.0 with positive consumer feedback.
  • NR is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).

What drags it down

  • Dose-evidence score of 5.3 is below average for the site.
  • Resveratrol (150mg is 30% of the 500mg trial dose) is significantly under-dosed.
  • Quercetin (200mg is 40% of the 500mg trial dose) is significantly under-dosed.
  • Betaine (TMG) (150mg is 5% of the 3000mg trial dose) is significantly under-dosed.
  • At $1.75/day it's on the expensive side.

Why you'd choose it

  • You want NR from a Thorne HealthTech product.
  • You prioritise tested by independent lab produkter with public lab certificates.

Why you might skip it

  • You need a full trial dose of resveratrol (this product under-doses it).
  • You want a cheaper option (this is $1.75/day).
Go deeper

Where this sits

Varumärke owners

Spot an error?

If you are the manufacturer or brand owner of ResveraCel and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primär sources, and publish any change with a dated note in the version history above. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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