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Study

Blueprint Protocol overview

Bryan Johnson / Blueprint

PRIMARY Tier 4 2026
DesignPRIMARY
TierTier 4, Ingredient RCT (different dose)
Year2026
Journalprotocol.bryanjohnson.com
N4
Added to NO1GEVITYMay 19, 2026

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12 encyclopedia entries reference this study.

MechanismAMPK ActivationMechanismAutophagyMechanismDNA Damage Response and Genomic InstabilityMechanismFOXO Longevity Transcription FactorsMechanismInsulin/IGF-1 Signaling in AgingMechanismDeregulated Nutrient SensingMechanismOxidative Stress and the Free Radical TheoryMechanismp53 Tumor Suppressor PathwayMechanismProteostasis CollapseMechanismStem Cell ExhaustionInterventionBlueprint ProtocolPersonBryan Johnson